Results 31 to 40 of about 65,509 (99)

Circ_0001206 regulates miR‐665/CRKL axis to alleviate hypoxia/reoxygenation‐induced cardiomyocyte injury in myocardial infarction

ESC Heart Failure, 2022
Myocardial infarction (MI) is a type of cardiovascular disease caused by myocardial necrosis. Growing evidences have suggested that circular RNAs (circRNAs) play crucial roles in cardiac hypoxia/reoxygenation (H/R)‐induced injury of MI.
Dongmei Wang, Limei Tian, Yan Wang, Xiaoli Gao, Hanbo Tang, J. Ge   +5 more
semanticscholar   +1 more source

Hsa_hsa_circ_0081069 promotes the progression of colorectal cancer through sponging miR‐665 and regulating E2F3 expression

Journal of clinical laboratory analysis (Print), 2022
Circular RNAs (circRNAs) have been implicated in the initiation and development of various cancers. This study explored the potential contribution of hsa_hsa_circ_0081069 in the progression of colorectal cancer (CRC).
Jingjing Xie, Danjuan Jin, Jinyin Xu, Fei Yang, Jianying Jin   +4 more
semanticscholar   +1 more source

Exosomal lncRNA SCIRT/miR-665 Transferring Promotes Lung Cancer Cell Metastasis through the Inhibition of HEYL

Journal of Oncology, 2021
Lung cancer remains the leading cause of cancer-related death worldwide. Recently, extracellular vesicles such as exosomes have attracted considerable interest both as a source for theranostic biomarkers and an essential participant in lung cancer ...
Zhengyang Wang, Minmin Lin, Lulu He, H. Qi, Jing Shen, K. Ying   +5 more
semanticscholar   +1 more source

miR-665 inhibits epithelial-to-mesenchymal transition in bladder cancer via the SMAD3/SNAIL axis

Cell Cycle, 2021
Emerging research indicates that miRNAs can regulate cancer progression by influencing molecular pathways. Here, we studied miR-665, part of the DLK1-DIO3 miRNA cluster, which is downregulated by upstream methylation in bladder cancer.
Weiyu Wang, Yufan Ying, Haiyun Xie, Jiangfeng Li, Xueyou Ma, Liujia He, Mingjie Xu, Shiming Chen, Haixiang Shen, Xiangyi Zheng, Ben Liu, Xiao Wang, Liping Xie   +12 more
semanticscholar   +1 more source

High-fructose corn syrup effects on metabolic parameters and malignancy

Journal of Diabetology, 2021
In the last century, eating habits have changed. Refined, unnatural, including high-carbohydrate and high-calorie, which have many chemical additives foods, are becoming our dietary habits. High-fructose corn syrup (HFCS) is one of the most commonly used
Yasin Simsek, Ulaş Serkan Topaloğlu, Oguzhan Sitki Dizdar   +2 more
doaj   +1 more source

Frailty predicts a higher risk of incident urolithiasis in 525 368 patients with diabetes mellitus: a population-based study

BMJ Open Diabetes Research & Care, 2020
ObjectivePatients with diabetes have an increased risk for urolithiasis, but the associated risk factors remain an active area of research. We investigated whether frailty influenced the probability of patients with diabetes developing urolithiasis ...
Chia-Ter Chao, Jui Wang, Kuan-Yu Hung
doaj   +1 more source

Knowledge on diabetes and its determinants among type 2 diabetic subjects in a low-resource setting: A cross-sectional study in a tertiary care hospital in Bangladesh

Journal of Diabetology, 2021
Background: Knowledge about diabetes is the cornerstone of self-management, which is crucial for diabetes care. Improving patients’ knowledge and self-management toward their condition can achieve better control, delay complications, and improve their ...
Mohammad Wahiduzzaman, Sharmin Hossain, Sahidul Md Islam, Friederike Banning, Liaquat Ali, Andres Lechner   +5 more
doaj   +1 more source

MiR-665 Regulates Vascular Smooth Muscle Cell Senescence by Interacting With LncRNA GAS5/SDC1

Frontiers in Cell and Developmental Biology, 2021
Background: Vascular aging is considered a special risk factor for cardiovascular diseases, and vascular smooth muscle cells (VSMCs) play a major role in aging-related vascular remodeling and in the pathological process of atherosclerosis.
Tianbin Chen, Qingyang Liang, Jialin Xu, Yanan Zhang, Yi Zhang, Liping Mo, Li Zhang   +6 more
semanticscholar   +1 more source

Rapid estradiol modulation of neuronal connectivity and its implications for disease

Frontiers in Endocrinology, 2011
Estrogens have multiple actions in the brain including modulating synaptic plasticity, connectivity and cognitive behaviours. While the classical view of estrogens are as endocrine signals, whose effects manifest via the regulation of gene transcription,
Deepak Prakash Srivastava, Peter ePenzes
doaj   +1 more source

Tissue inhibitor matrix metalloproteinase 1 and risk of type 2 diabetes in a Chinese population

BMJ Open Diabetes Research & Care, 2020
IntroductionThe non-invasive enhanced liver fibrosis (ELF) score—comprising tissue inhibitor of matrix metalloproteinases-1 (TIMP1), hyaluronic acid (HA) and amino-terminal propeptide of type III procollagen (PIIINP)—has been shown to accurately predict ...
Yeli Wang
doaj   +1 more source