Results 71 to 80 of about 66,192 (99)

MicroRNA-665 Regulates Cell Proliferation and Apoptosis of Vascular Smooth Muscle Cells by Targeting TGFBR1.

International Heart Journal, 2021
Coronary artery disease (CAD) is one of the heavy health burdens worldwide. Aberrant proliferation of vascular smooth muscle cells (VSMCs) contributes to the occurrence and development of CAD.
Lang Wang, Jiali Zhou, F. Guo, T. Yao, Liang Zhang   +4 more
semanticscholar   +1 more source

Downregulation of MIAT reduces the proliferation and migratory and invasive abilities of retinoblastoma cells by sponging miR-665 and regulating LASP1.

Experimental and Therapeutic Medicine, 2021
Long non-coding RNAs (lncRNAs) can function as onco-lncRNAs in several types of human cancer, including retinoblastoma (Rb). The present study investigated the potential role and regulatory mechanism of the lncRNA myocardial infarction-associated ...
Xiabing Xu, Yadong Zhao, Gang Duan, Bo Du   +3 more
semanticscholar   +1 more source

MiR-155 and MiR-665 Role as Potential Non-invasive Biomarkers for Hepatocellular Carcinoma in Egyptian Patients with Chronic Hepatitis C Virus Infection

Journal of Translational Internal Medicine, 2020
Background and Objectives Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer associated death globally. Serum micro RNAs are full of potential as noninvasive biomarkers.
A. Mohamed, A. A. Omar, Rehab R. El-Awady, S. Hassan, Waleed Mohamed Soliman Eitah, R. Ahmed, A. Khater, Omnia Tantawi, A. Mohamed   +8 more
semanticscholar   +1 more source

LEF1 mediates osteoarthritis progression through circRNF121/miR-665/MYD88 axis via NF-кB signaling pathway

Cell Death and Disease, 2020
Osteoarthritis (OA) is a joint disease that causes great pain to patients and imposes a tremendous burden on the world’s medical resources. Regulatory noncoding RNAs, including circular RNAs (circRNAs) and microRNAs (miRNAs), play an important role in OA
Tianfu Wang, Zhiyu Hao, Changcheng Liu, Lebin Yuan, Li Li, Menghong Yin, Qing Li, Zhiming Qi, Zi Wang   +8 more
semanticscholar   +1 more source

miR-665 expression predicts poor survival and promotes tumor metastasis by targeting NR4A3 in breast cancer

Cell Death and Disease, 2019
Cancer metastasis is the main cause of death in breast cancer (BC) patients. Therefore, prediction and treatment of metastasis is critical for enhancing the survival of BC patients.
Xinge Zhao, Jing-Ye Hu, Jun Tang, W. Yi, Mei-yin Zhang, R. Deng, S. Mai, Nuoqing Weng, Rui-Qi Wang, Ji Liu, Huizhong Zhang, Jie-hua He, Hui‐Yun Wang   +12 more
semanticscholar   +1 more source

Review of American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis.

Клиническая и экспериментальная тиреоидология, 2017
Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions and patient preference.
Valentin V. Fadeyev
doaj   +1 more source

Interrelation specific autoimmune pathologies of a thyroid gland with inorganic autoimmune rheumatic diseases

Клиническая и экспериментальная тиреоидология, 2012
The problem of a pathology of a thyroid gland at rheumatic diseases, in particular at rheumatoid arthritis, remains actual and to this day. The work purpose was studying antitelogenesis to thyroid hormones at patients with mixt autoimmune pathology.

doaj   +1 more source

Detection of BRAF Gene Mutation in Preoperative Diagnostic of Thyroid Gland Cancer

Клиническая и экспериментальная тиреоидология, 2009
Purpose: To assess the utility of BRAFV600E mutation detection in preoperative thyroid cancer diagnostic. Material and methods: We studied 46 aspirates taken by FNA from patients with thyroid gland nodes.

doaj   +1 more source

Treatment of Subclinical Hypothyroidism in Obese Patients

Клиническая и экспериментальная тиреоидология, 2008
We observed 20 women suffering from adiposity and subclinical hypothyroidism. Lipid spectrum, carbohydrate metabolism, BP and insulinresistance, the extent and variants of fat tissue distribution, a test with physical exercise, all research in dynamics ...

doaj   +1 more source

Cytokine Status, Thyroid Autoantibodies and Their Dynamic Changes During the Treatment of Graves' Disease

Клиническая и экспериментальная тиреоидология, 2008
It has been found during the research that the changes of Th1 and Th2 marker cytokine content in Graves Disease are dynamic and are directly correlated not only with the severity of autoimmune thyrotoxicosis, but also with the method of treatment used ...

doaj   +1 more source