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Anti-BCMA BiTE® AMG 701 Potently Induces Specific T Cell Lysis of Human Multiple Myeloma (MM) Cells and Immunomodulation in the Bone Marrow Microenvironment

Blood, 2018
The first Bispecific T-cell Engager (BiTE®) targeting B-cell maturation antigen (BCMA) on multiple myeloma (MM) cells and CD3 on T cells is currently in clinical development (NCT02514239).
Shih-Feng Cho   +9 more
semanticscholar   +1 more source

Histone Deacetylase 701 (HDT701) Induces Flowering in Rice by Modulating Expression of OsIDS1

Molecules and Cells, 2018
Rice is a facultative short-day (SD) plant in which flowering is induced under SD conditions or by other environmental factors and internal genetic programs. Overexpression of Histone Deacetylase 701 (HDT701) accelerates flowering in hybrid rice. In this
Lae-Hyeon Cho   +3 more
semanticscholar   +1 more source

Is Your Career Hurting You? The Ergonomic Consequences of Surgery in 701 Urologists Worldwide

Journal of endourology, 2017
Purpose: Our objective was to seek correlations between the type, volume, and duration of surgical work performed, surgeon habits and characteristics, and the prevalence of neck and back musculoskeletal complaint and intervention across career from ...
G. Lloyd   +5 more
semanticscholar   +1 more source

Abstract 744: ADCT-701, a novel pyrrolobenzodiazepine (PBD) dimer-based antibody-drug conjugate (ADC) targeting DLK1-expressing tumors

Experimental and Molecular Therapeutics, 2018
Delta-like 1 homolog protein (DLK-1) is an EGF-like membrane bound protein consisting of six tandem EGF-like repeats, a juxtamembrane region with a TACE (ADAM17)-mediated cleavage site, a transmembrane domain, and a short intracellular tail.
F. Zammarchi   +12 more
semanticscholar   +1 more source

AMG 701, a half-life extended anti-BCMA BiTE®, potently induces T cell-redirected lysis of human multiple myeloma cells and can be combined with IMiDs to overcome the immunosuppressive bone marrow microenvironment

Clinical Lymphoma, Myeloma & Leukemia, 2019
Shih-Feng Cho   +10 more
semanticscholar   +1 more source

RESPONSE TO AIDAN DODSON: ASSESSING THE STRENGTH OF THE TWENTY-FIFTH DYNASTY’S ARMY IN 701 BCE

Jerusalem's Survival, Sennacherib's Departure, and the Kushite Role in 701 BCE, 2020

semanticscholar   +1 more source

RESPONSE TO ALAN B. LLOYD: WHY MINIMIZE THE KUSHITE ROLE IN 701 BCE?

Jerusalem's Survival, Sennacherib's Departure, and the Kushite Role in 701 BCE, 2020

semanticscholar   +1 more source

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