Results 11 to 20 of about 162,445 (96)

Por que publicar em periódicos nacionais?

Arquivos Brasileiros de Cardiologia, 2012
A relutância dos autores brasileiros em publicar em revistas brasileiras é histórica e não mais se justifica. Atualmente, vários periódicos brasileiros estão indexados em bases internacionais, cujas versões em inglês permitem a divulgação de nossos ...
Max Grinberg, Maria Cecília Solimene, Maria do Carmo Cavarette Barreto   +2 more
doaj   +1 more source

A Phase 1 First in Human (FIH) Study of AMG 701, an Anti-B-Cell Maturation Antigen (BCMA) Half-Life Extended (HLE) BiTE® (bispecific T-cell engager) Molecule, in Relapsed/Refractory (RR) Multiple Myeloma (MM)

, 2020
Aims: To evaluate AMG 701, a BiTE® molecule binding BCMA on MM cells and CD3 on T cells, in RR MM (Amgen, NCT03287908); primary objective was to evaluate safety and tolerability and estimate a biologically active dose; secondary objectives were to ...
S. Harrison, M. Minnema, Hans C. Lee, A. Spencer, P. Kapoor, D. Madduri, J. Larsen, S. Ailawadhi, J. Kaufman, M. Raab, P. Hari, S. Iida, R. Vij, F. Davies, R. Lesley, V. Upreti, Zhao Yang, Anjali Sharma, A. Minella, S. Lentzsch   +19 more
semanticscholar   +1 more source

Significant Regional Differences in Antibiotic Use Across 576 US Hospitals and 11 701 326 Adult Admissions, 2016–2017

Clinical Infectious Diseases, 2020
Background Quantifying the amount and diversity of antibiotic use in United States hospitals assists antibiotic stewardship efforts but is hampered by limited national surveillance.
K. Goodman, S. Cosgrove, Lisa Pineles, L. Magder, D. Anderson, E. D. Dodds Ashley, R. Polk, H. Quan, W. Trick, K. Woeltje, S. Leekha, A. Harris   +11 more
semanticscholar   +1 more source

AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeys.

Blood Advances, 2020
Multiple myeloma (MM) is a hematologic malignancy that is characterized by the accumulation of abnormal plasma cells (PCs) in the bone marrow (BM). Patient outcome may be improved with BiTE (bispecific T-cell engager) molecules, which redirect T cells to
R. Goldstein, A. Goyos, Chi-Ming Li, Petra Deegen, P. Bogner, Alexander Sternjak, O. Thomas, M. Klinger, J. Wahl, M. Friedrich, B. Rattel, Edwin Lamas, Xiao Min, A. Sudom, Mozhgan Farshbaf, A. Coxon, M. Balazs, T. Arvedson   +17 more
semanticscholar   +1 more source

Investigation of optimal position for implantable loop recorders by potential mapping with Reveal DX

Journal of Arrhythmia, 2015
Background: Electrode positioning is important for the operation of implantable loop recorders (ILRs). This study aimed to investigate optimal electrode positions for the implantation of ILRs.
Akira Kawashima, Fumi Tanimoto, Tsuyoshi Nagao, Takeshi Toyoshima, Yuji Okuyama, MD, PhD   +4 more
doaj   +1 more source

Successful autologous skin grafting in a patient of severe Haemophilia

Journal of Applied Hematology, 2016
In haemophilia-A patients, if the plasma concentration of factor VIII could be maintained at an optimum level, an open wound can be easily covered with split-thickness skin grafting without any significant bleeding or complication.
Rahul Gorka, Elvino Barreto, Geley Ete
doaj   +1 more source

Brazilian cardio-oncology: the 10-year experience of the Instituto do Cancer do Estado de Sao Paulo

BMC Cardiovascular Disorders, 2020
Background In recent years, the field of cardio-oncology has grown worldwide, bringing benefits to cancer patients in terms of survival and quality of life.
Isabela B. S. da S. Costa, Cristina S. Bittar, Silvia M. R. Fonseca, Carolina M. P. D. e Silva, Marilia H. H. dos Santos Rehder, Stéphanie I. Rizk, Cecilia B. B. V. Cruz, Clara S. Figueiredo, Fernanda T. de A. Andrade, Ludmila de A. Barberino, Fernanda A. de S. Costa, Letticya P. Machado, Thalita B. González, Marcel P. C. Almeida, Julia T. Fukushima, Roberto Kalil Filho, Ludhmila Abrahao Hajjar   +16 more
doaj   +1 more source

Non-invasively measured central and peripheral factors of oxygen uptake differ between patients with chronic heart failure and healthy controls

BMC Cardiovascular Disorders, 2020
Background Maximum oxygen uptake is an established measurement of diagnosing chronic heart failure and underlies various central and peripheral factors.
Joana Brochhagen, Michael Thomas Coll Barroso, Christian Baumgart, Jürgen Freiwald, Matthias Wilhelm Hoppe   +4 more
doaj   +1 more source

Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study [PDF]

Journal of Stroke, 2020
Background and Purpose Liver enzymes (aspartate aminotransferase [AST], alanine aminotransferase [ALT], and gamma-glutamyl transpeptidase [GGT]) are glutamate-regulatory enzymes, and higher glutamate levels correlated with worse prognosis of patients ...
Angela Ruban, Natalie Daya, Andrea L.C. Schneider, Rebecca Gottesman, Elizabeth Selvin, Josef Coresh, Mariana Lazo, Silvia Koton   +7 more
doaj   +1 more source

Identification, Cloning and Heterologous Expression of the Gene Cluster Directing RES-701-3, -4 Lasso Peptides Biosynthesis from a Marine Streptomyces Strain

Marine Drugs, 2020
RES-701-3 and RES-701-4 are two class II lasso peptides originally identified in the fermentation broth of Streptomyces sp. RE-896, which have been described as selective endothelin type B receptor antagonists. These two lasso peptides only differ in the
D. Oves-Costales, M. Sánchez-Hidalgo, Jesús Martín, O. Genilloud   +3 more
semanticscholar   +1 more source