Results 11 to 20 of about 169,093 (102)
Blood Advances, 2020 We investigated here the novel immunomodulation and anti-multiple myeloma (MM) function of T cells engaged by the bispecific T-cell engager molecule AMG 701, and further examined the impact of AMG 701 in combination with immunomodulatory drugs (IMiDs ...
Shih-Feng Cho +13 more
semanticscholar +1 more source
Clinical Infectious Diseases, 2020 Background Quantifying the amount and diversity of antibiotic use in United States hospitals assists antibiotic stewardship efforts but is hampered by limited national surveillance.
K. Goodman +11 more
semanticscholar +1 more source
Blood Advances, 2020 Multiple myeloma (MM) is a hematologic malignancy that is characterized by the accumulation of abnormal plasma cells (PCs) in the bone marrow (BM). Patient outcome may be improved with BiTE (bispecific T-cell engager) molecules, which redirect T cells to
R. Goldstein +17 more
semanticscholar +1 more source
, 2020 Aims: To evaluate AMG 701, a BiTE® molecule binding BCMA on MM cells and CD3 on T cells, in RR MM (Amgen, NCT03287908); primary objective was to evaluate safety and tolerability and estimate a biologically active dose; secondary objectives were to ...
S. Harrison +19 more
semanticscholar +1 more source
Marine Drugs, 2020 RES-701-3 and RES-701-4 are two class II lasso peptides originally identified in the fermentation broth of Streptomyces sp. RE-896, which have been described as selective endothelin type B receptor antagonists. These two lasso peptides only differ in the
D. Oves-Costales +3 more
semanticscholar +1 more source
Validation of the Duke Activity Status Index questionnaire by telephone In individuals after stroke
International Journal of Cardiology. Cardiovascular Risk and Prevention, 2023 Background: Due to social restrictions caused by the pandemic, there was a need to validate outcome measures that could be administered by telephone call.
Camila Dias +4 more
doaj +1 more source
International Journal of Cardiology. Cardiovascular Risk and Prevention, 2023 Background: Intermittent fasting may increase longevity and lower cardiometabolic risk. This study evaluated whether fasting modifies clinical risk scores for mortality [i.e., Intermountain Mortality Risk Score (IMRS)] or chronic diseases [e.g., Pooled ...
Benjamin D. Horne +7 more
doaj +1 more source
Oral nitrate-reducing bacteria as potential probiotics for blood pressure homeostasis
Frontiers in Cardiovascular MedicineHypertension is a leading cause of morbidity and mortality worldwide and poses a major risk factor for cardiovascular diseases and chronic kidney disease.
Xiaofen Chai, Libing Liu, Feng Chen
doaj +1 more source
Socioeconomic factors and long-term mortality risk after surgical aortic valve replacement
International Journal of Cardiology. Cardiovascular Risk and Prevention, 2023 Background: There is scarce knowledge about the association between socioeconomic status and mortality in patients undergoing surgical aortic valve replacement.
Maria Lachonius +7 more
doaj +1 more source
Case Report: Abdominal surgery with the support of Impella (SURGELLA), a new frontier to be explored
Frontiers in Cardiovascular MedicineA 74-year-old man with advanced heart failure was admitted to the hospital with a diagnosis of colorectal cancer, and he underwent surgery. To maintain stable hemodynamics, the Impella CP device was used.
Stefano Guarracini +9 more
doaj +1 more source