Results 11 to 20 of about 177,998 (114)

Multi-institutional retrospective study investigating blood culture protocols and test positivity in 701 dogs

Frontiers in Veterinary Science, 2023
Objectives (i) To determine the influence of specimen collection protocol (timing and specimen quantity), primary disease process, and pre-existing antimicrobial or immunosuppressive therapy on blood culture (BC) positivity and (ii) To determine ...
Andrzej J. Ogrodny, Rinosh Mani, Sarah M. Schmid, Emily N Gould, C. Fellman, Ian M DeStefano, S. Shropshire, Jillian M. Haines, T. Bolton, Sara A Jablonski, Nicole Jess, H. Cridge   +11 more
semanticscholar   +1 more source

Implementasi Standar Audit (SA) 701: Pengomunikasian Hal Audit Utama di Tahun Pertama Penerapan

Jurnal Akuntansi Manado (JAIM), 2023
Penelitian ini bertujuan untuk menganalisis bagaimana implementasi SA 701 dan apa saja kendala yang dihadapi auditor dalam implementasi SA 701 di tahun pertama penerapannya.
Marina Lauren, Aria Farah Mita
semanticscholar   +1 more source

Efficacy and safety of a new ranibizumab biosimilar CKD-701 using a pro re nata treatment regimen in neovascular age-related macular degeneration: A phase 3 randomized clinical trial

PLoS ONE, 2022
Purpose This study aimed to establish the efficacy, safety, and immunogenicity equivalence of the proposed biosimilar CKD-701 with the reference ranibizumab in patients with treatment-naïve neovascular age-related macular degeneration (nAMD).
C. Yoon, Jaeryung Oh, K. Bae, Un Chul Park, K. Yu, H. Yu   +5 more
semanticscholar   +1 more source

INZ‐701, a recombinant ENPP1 enzyme, prevents ectopic calcification in an Abcc6−/− mouse model of pseudoxanthoma elasticum

Experimental Dermatology, 2022
Pseudoxanthoma elasticum (PXE), a heritable multisystem ectopic calcification disorder, is predominantly caused by inactivating mutations in ABCC6. The encoded protein, ABCC6, is a hepatic efflux transporter and a key regulator of extracellular inorganic
I. Jacobs, Zhiliang Cheng, D. Ralph, K. O’Brien, Lisa Flaman, J. Howe, David Thompson, J. Uitto, Qiaoli Li, Y. Sabbagh   +9 more
semanticscholar   +1 more source

INZ‐701 Prevents Ectopic Tissue Calcification and Restores Bone Architecture and Growth in ENPP1‐Deficient Mice

Journal of Bone and Mineral Research, 2021
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is the major enzyme that cleaves extracellular adenosine triphosphate (ATP) to generate pyrophosphate (PPi), an inorganic metabolite with potent anticalcification activity.
Zhiliang Cheng, K. O’Brien, J. Howe, C. Sullivan, D. Schrier, A. Lynch, S. Jungles, Y. Sabbagh, D. Thompson   +8 more
semanticscholar   +1 more source

A Phase 1 First in Human (FIH) Study of AMG 701, an Anti-B-Cell Maturation Antigen (BCMA) Half-Life Extended (HLE) BiTE® (bispecific T-cell engager) Molecule, in Relapsed/Refractory (RR) Multiple Myeloma (MM)

, 2020
Aims: To evaluate AMG 701, a BiTE® molecule binding BCMA on MM cells and CD3 on T cells, in RR MM (Amgen, NCT03287908); primary objective was to evaluate safety and tolerability and estimate a biologically active dose; secondary objectives were to ...
S. Harrison, M. Minnema, Hans C. Lee, A. Spencer, P. Kapoor, D. Madduri, J. Larsen, S. Ailawadhi, J. Kaufman, M. Raab, P. Hari, S. Iida, R. Vij, F. Davies, R. Lesley, V. Upreti, Zhao Yang, Anjali Sharma, A. Minella, S. Lentzsch   +19 more
semanticscholar   +1 more source

Significant Regional Differences in Antibiotic Use Across 576 US Hospitals and 11 701 326 Adult Admissions, 2016–2017

Clinical Infectious Diseases, 2020
Background Quantifying the amount and diversity of antibiotic use in United States hospitals assists antibiotic stewardship efforts but is hampered by limited national surveillance.
K. Goodman, S. Cosgrove, Lisa Pineles, L. Magder, D. Anderson, Elizabeth S. Dodds Ashley, R. Polk, H. Quan, W. Trick, K. Woeltje, S. Leekha, A. Harris   +11 more
semanticscholar   +1 more source

EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers

Pharmacology Research & Perspectives, 2021
Targeting the first protein complex of the mitochondrial electron transport chain (MC1) in cancer has become an attractive therapeutic approach in the recent years, given the metabolic vulnerabilities of cancer cells. The anticancer effect exerted by the
Raquel Luna Yolba, V. Visentin, C. Hervé, J. Chiche, J. Ricci, J. Méneyrol, Michael R Paillasse, N. Alet   +7 more
semanticscholar   +1 more source

Short-term Outcomes of Ranibizumab Biosimilar CKD-701 Treatment in Macular Edema Secondary to Retinal Vein Occlusion

Journal of the Korean Ophthalmological Society
Purpose: To evaluate the short-term outcomes of intravitreal injection therapy using the ranibizumab biosimilar CKD-701 in macular edema due to retinal vein occlusion.Methods: We conducted a retrospective analysis of medical records from patients ...
Daeun Shin, Yeji Kim, Jae Hui Kim
semanticscholar   +1 more source

AMG 701 Potently Induces Anti-Multiple Myeloma (MM) Functions of T Cells and IMiDs Further Enhance Its Efficacy to Prevent MM Relapse In Vivo

Blood, 2019
AMG 701 is a half-life extended BiTE® (bispecific T-cell engager) targeting the B cell maturation antigen (BCMA). Here, we confirmed AMG 701-mediated T cell-redirected lysis of MM cells, defined immunomodulatory effects of AMG 701, and investigated ...
Shih-Feng Cho, Liang Lin, Lijie Xing, Kenneth Wen, Tengteng Yu, Phillip A. Hsieh, Yuyin Li, N. Munshi, J. Wahl, Katja Matthes, K. Anderson, Tara L. Chapman-Arvedson, Y. Tai   +12 more
semanticscholar   +1 more source