Results 41 to 50 of about 191,022 (315)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Seismic Damage Probability Assessment of Existing Reinforced Concrete School Buildings in Afghanistan

Buildings
Existing Reinforced Concrete School buildings with low earthquake resistance may suffer structural failure or severe damage in a catastrophic seismic event. Ascertaining earthquake resistance in existing school buildings is vital to confirming the safety
Sayed Qudratullah Sharafi, Taiki Saito
doaj   +1 more source

Effect of beam-column joints flexibility on the seismic response of setback RC buildings designed according to the Algerian seismic code

Fracture and Structural Integrity, 2022
The Algerian seismic code assumes that the beam-column joints in monolithic reinforced concrete (RC) buildings are fully rigid. However, many experiments have proven the existence of relative rotations in these connections, and then the presence of ...
Abdallah Yacine Rahmani, Said Hicham Boukhalkhal�, Mohamed Badaoui   +2 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Inelastic seismic response of RC building with control system. [PDF]

, 2011
Conventional buildings are mainly designed based on elastic analysis of structures subjected to moderate earthquakes. In this case, the seismic forces are much smaller than the forces introduced by strong ground motions with the considered structural ...
Abang Ali, Abang Abdullah, Hejazi, Farzad, Jaafar, Mohd Saleh, Kojouri, Samira Jilani, Noorzaei, Jamaloddin, Thanoon, Waleed Abdulmalik   +5 more
core   +1 more source

An Accurate Numerical Model Simulating Hysteretic Behavior of Reinforced Concrete Columns Irrespective of Types of Loading Protocols

International Journal of Concrete Structures and Materials, 2021
In older reinforced concrete (RC) buildings, columns are fragile elements that can induce collapse of entire buildings during earthquakes. An accurate assessment of the seismic vulnerability of RC buildings using nonlinear response history analyses ...
Chang Seok Lee, Sang Whan Han
doaj   +1 more source

Common irregularities and its effects on reinforced concrete building response

Structural Mechanics of Engineering Constructions and Buildings, 2021
In most of the countries, the irregular building construction is popular for fulfilling both aesthetic and functional requirements. However, the evidence of past earthquakes in Nepal and the globe demonstrated the higher level of seismic vulnerability of
Krishna Ghimire, Hemchandra Chaulagain
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Buildings in Barcelona protected from railway-induced vibrations with base isolation [PDF]

, 2014
This work describes two mid-height RC base isolated buildings recently erected in Barcelona. Both buildings are located near the main railway station in Barcelona (Barcelona-Sants), thus undergoing dynamic excitations due to intensive railway traffic ...
Araníbar, Hugo, Caselles Magallón, Josep Oriol, Clapés Boixader, Jaume, Eskubi Ugarte, Ignacio, López Almansa, Francisco, Mas, Cristina, Roca Fabregat, Pedro   +6 more
core  

Untersuchungen an mit Mauerwerk ausgefachten Stahlbetonrahmen und neue Lösungsvorschläge [PDF]

, 2016
The vulnerability of unreinforced masonry walls (URM) under seismic events, causing huge loss of money and human lives, has revealed the enormous need for an efficient strengthening material.
Leite, João Miguel Carvalho, Lourenço, Paulo B., Pereira, Paulo, Vasconcelos, Graça   +3 more
core   +1 more source