Results 141 to 150 of about 15,146 (243)

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Journal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads, Megan H. Hagenauer, Jinglin Xiong, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Elizabeth Flandreau, Stanley Watson Jr., Huda Akil   +8 more
wiley   +1 more source

Bioprosthetic Aortic Valve Thrombosis Presenting as Recurrent Inferior Wall STEMI. [PDF]

JACC Case Rep
Kittiboonya T, Leelasithorn S, Chandavimol M, Sasiprapha T, Kongrat S, Methachittiphan N.   +5 more
europepmc   +1 more source

A Systematic Review and Meta‐Analysis of Semaglutide Effects on Adipose Tissue and Emerging Effects on Brain and Cognition

Obesity Reviews, EarlyView.
ABSTRACT Background In 2023 and 2024, research into semaglutide (SEMA), an antiobesity and antidiabetic medication, indicated potential benefits beyond its approved uses, particularly in preventing Alzheimer's disease (AD). This highlights the link between obesity and AD development.
Amene Saghazadeh, Mahsa Dolatshahi, Soheil Mohammadi, Sara Hosseinzadeh Kassani, Mahshid Naghashzadeh, Joseph E. Ippolito, Claude B. Sirlin, Bettina Mittendorfer, Matthew R. Brier, Suzanne E. Schindler, John C. Morris, Danny Mou, Hani Charles Soudah, Tammie L. S. Benzinger, Cyrus A. Raji   +14 more
wiley   +1 more source

Resorbable Magnesium Scaffold Use in STEMI: A Case Series With Interval Imaging Analysis. [PDF]

JACC Case Rep
Fung CY, Chung TS.
europepmc   +1 more source

Serial Spatial Transcriptomes Reveal Regulatory Transitions in Maize Leaf Development

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant leaves originate from the shoot apical meristem (SAM) and undergo a developmental process of highly coordinated gene expression regulation. To date, only a few key regulators have been identified and characterised, so the gene expression cascades responsible for leaf cell specification and differentiation from SAM remain largely elusive.
Chi‐Chih Wu, Ludvig Larsson, Kun‐Ting Hsieh, Chun‐Ping Yu, Yi‐Hua Chen, Kai‐Hsuan Ding, Ho‐Chun Yang, Joakim Lundeberg, Chin‐Min Kimmy Ho, Shu‐Hsing Wu, Mei‐Yeh Jade Lu, Wen‐Hsiung Li   +11 more
wiley   +1 more source

Prognostic value of lesion-specific and proximal coronary segment pericoronary adipose tissue CT Attenuation in ischemic heart disease with angina pectoris. [PDF]

Sci Rep
Wang L, He W, Jiang S, Su K, Tang Y, Pang C, Chen X, Liu X, Li R.   +8 more
europepmc   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

Application of low-dose "one-stop" myocardial computed tomography perfusion imaging in coronary artery disease. [PDF]

Quant Imaging Med Surg
Hu Y, Peng W, Liu K, Xu X, Hu S, Lyu X, Liu X, Qin M, Sun R, Ren W, Zhao L, Xia C.   +11 more
europepmc   +1 more source

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source

Transcriptional benchmark dose modeling of ultraviolet radiation‐induced genomic activation in mouse skin

Photochemistry and Photobiology, EarlyView.
Exposure to ultraviolet radiation (UV‐R) from tanning equipment increases skin cancer risk through molecular changes, but genomic thresholds remain unclear. Using mice, we examined dose‐ and time‐dependent gene expression after erythemally‐weighted UV‐R doses (0–40 mJ/cm2).
Sami S. Qutob, Samantha P. M. Roesch, Sandy Smiley, Pascale V. Bellier, Andrew Williams, Kate B. Cook, Matthew J. Meier, Andrea Rowan‐Carroll, Carole L. Yauk, James P. McNamee, Vinita Chauhan   +10 more
wiley   +1 more source