Results 181 to 190 of about 160,488 (298)

Prediction of dose reductions and impact of reduced starting doses of CDK4/6i on effectiveness in HR‐positive/HER2‐negative metastatic breast cancer: Real‐world data from the OPAL registry

open access: yesInternational Journal of Cancer, Volume 159, Issue 1, Page 244-256, 1 July 2026.
What's New? Balancing efficacy and tolerability is challenging in oncology, as standard dosing often prioritizes maximum tolerated doses over other patient needs. Here, the authors developed a predictive index to identify patients with increased probability of dose reduction in metastatic breast cancer and compared the real‐world effectiveness of ...
Patrick Marschner   +19 more
wiley   +1 more source

The Challenges of Domestic Wastewater/Sewage Systems for Māori Communities

open access: yesKōtuitui: New Zealand Journal of Social Sciences Online, Volume 21, Issue 2, June 2026.
The development of domestic wastewater systems in contemporary Aotearoa New Zealand has presented a significant challenge for Māori communities. While those communities have supported attempts to address the pollution of land and waterways through modern treatment methods, the solution has included continuing discharges of sometimes untreated and often
Martin Fisher, Shaun Ogilvie
wiley   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao   +4 more
wiley   +1 more source

Oncofertility in Women with Renal Cell Carcinoma in the Immune Checkpoint Inhibitors Era: A Multidisciplinary Perspective. [PDF]

open access: yesJ Clin Med
Miscia M   +13 more
europepmc   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong   +4 more
wiley   +1 more source

Evaluating the Innovator Training Program: Strengthening Evidence‐Based Practice and Building Implementation Capability in the Australian Aged Care Workforce

open access: yesAustralasian Journal on Ageing, Volume 45, Issue 2, June 2026.
ABSTRACT Objectives This study evaluated the outcomes for individuals who completed an Innovator Training Program (ITP) funded by the Commonwealth Government of Australia and delivered by Aged Care Research & Industry Innovation Australia (ARIIA). The program was designed to build best‐practice implementation and change management capability among the ...
Stephanie Champion   +2 more
wiley   +1 more source

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