Results 201 to 210 of about 160,488 (298)

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes at Aβ‐PET Centiloid 15, Mean Age of 66 Years

open access: yesAnnals of Neurology, Volume 99, Issue 5, Page 1327-1342, May 2026.
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas   +29 more
wiley   +1 more source

Metachronous bilateral renal cancer with immune checkpoint blockade-mediated eradication of bone metastasis: case report. [PDF]

open access: yesFront Oncol
Metodiev D   +8 more
europepmc   +1 more source

Urinary microbiota diversity and composition in patients with advanced renal cell cancer

open access: yesBJUI Compass, Volume 7, Issue 5, May 2026.
Abstract Objectives This study aims to investigate the role of urinary microbiota in renal cell carcinoma; we analysed urinary microbiota in kidney cancer patients and explored its potential role as biomarker. Subjects and methods Samples were collected from 49 males (28 patients planned to undergo systemic therapy and 21 healthy volunteers).
Frederico Leal   +7 more
wiley   +1 more source

Multi‐Transcriptomic Analysis Reveals That EREG‐Driven TME Crosstalk Defines Anti‐EGFR Response in Colorectal Cancer

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
A multi‐transcriptomic analysis reveals the “EREG/EGFR/CSF axis” as a key intercellular network in the tumor microenvironment that dictates anti‐EGFR sensitivity in colorectal cancer. ABSTRACT Sidedness influences colorectal cancer (CRC) prognosis and treatment response, yet the mechanism dictating differential EGFR inhibitor (EGFRI) sensitivity is ...
Atsuki Taniguchi   +9 more
wiley   +1 more source

DNA methyltransferase inhibition is a therapeutic vulnerability in VHL-deficient renal cell carcinoma cells. [PDF]

open access: yesExp Mol Med
Pu Y   +15 more
europepmc   +1 more source

Differentiation of Fat‐Poor Renal Angiomyolipoma From Clear Cell Renal Cell Carcinoma: Diagnostic Performance of a Novel Type of Color Contrast Enhanced Ultrasound

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
Our study confirms CPI can distinguish AML.wovf from ccRCC, potentially helping patients with AML.wovf avoid unnecessary surgery. These findings expand CPI's clinical utility, providing a promising tool for diagnosing renal tumors. ABSTRACT Background The similar imaging characteristics of renal angiomyolipoma without visible fat (RAML.wvf) and clear ...
Yiman Du   +5 more
wiley   +1 more source

Different Immune Cells Modified With Chimeric Antigen Receptors Are Being Applied to Ovarian Cancer: Which Is the Most Effective?

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang   +4 more
wiley   +1 more source

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