Results 41 to 50 of about 386 (145)

117 COVID-19 RCEM research summaries: taking the burden off busy clinicians

Emergency Medicine Journal, 2020
Aims/Objectives/BackgroundEntering lockdown on 23rd March 2020 due to the COVID-19 pandemic marked an unprecedented period for healthcare evidence. An exponential increase in published work, pre-prints, guidelines, online information portals and more, has been overwhelming especially when combined with the ever-changing local emergency department ...
Reynard, Charles, Jafar, Anisa, Oliver, Govind, Darbyshire, Daniel, Prager, Gabrielle, Naguib, Mina, Carley, Simon   +6 more
openaire   +1 more source

Applications and Challenges of Epigenetic Signature Detection in the Diagnostic Genomics Laboratory–Current and Future Directions

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Background Epigenetic signature detection (ESD) identifies disease‐associated DNA methylation patterns and offers valuable insights beyond traditional genomic testing. Episignatures are increasingly recognised for their diagnostic potential, particularly in rare and complex disorders where conventional sequencing falls short.
Amy Harte, Preeti Khetarpal
wiley   +1 more source

A Population‐Based Study of Limb Body Wall Complex With Proposed Features for Prenatal Diagnosis

American Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Limb body wall complex (LBWC) is a lethal condition comprising major congenital anomalies. Although currently diagnosed in the early prenatal period, historical diagnostic criteria are based on detailed pathological assessments. Prenatal and postnatal findings of LBWC and their phenotypic overlap with body stalk anomaly (BSA) and recurrent ...
Mary Ann Thomas, Susan Crawford, Tanya Bedard   +2 more
wiley   +1 more source

What Proportion of Emergency Department Headache Patients With Normal Neurology Have a Serious Secondary Headache Cause? A HEAD Study Report

Emergency Medicine Australasia, Volume 37, Issue 5, October 2025.
ABSTRACT Objectives To estimate the proportion of Emergency Department (ED) headache patients without neurological features who are diagnosed with a serious secondary headache cause. Methods Unplanned secondary analysis of HEAD Study/HEAD Colombia data.
Anne Maree Kelly, Kevin H. Chu, Win Sen Kuan, Gerben Keijzers, Frances B. Kinnear, Alejandro Cardozo‐Ocampo, on behalf of the HEAD Study and HEAD Colombia Investigators, Catherine Lunter, Rochelle Facer, David Thomson, Robert Day, Greg McDonald, Sarah Jones, Julian Cochrane, Stephen Gourley, Mark Ross, Vinay Gangathimmaiah, Kim Hansen, Frances B. Kinnear, Gerben Keijzers, Kevin Chu, Paul Bowe, Raymund de la Cruz, Daniel Haustead, Jean Moller, Katie Walker, Richard D. Smith, Ron Sultana, John Pasco, Neil Goldie, Andis Graudins, Rosamond Dwyer, George Plunkett, Anne‐Maree Kelly, Hugh Mitenko, Michael Lovegrove, Ben Smedley, Colin A. Graham, Ling Yan Leung, Win Sen Kuan, Ying Wei Yau, Wei Ming Ng, Ranjeev Kumar, Dennis Wen Jie Chia, Said Laribi, Mounir Hilal, Rarthtana Mil, Audrey Gerineau, Matthew J. Reed, Daniel Horner, Edward Carlton, Tom Roberts, Girish Boggaram, Jayne Foot, Andy Appleboam, Rachel Goss, Hamza Malik, Richard Body, John‐Paul Williamson, Adela Golea, Sonia Luka, Huseyin Avni Demir, Şafak Öner Gülpinar, Lale Tolu, Muhammet Hacimustafaoğlu, Mehmet A. Karamercan, Elif Çelikel, Çilem Çaltili, Selahattin Gürü, Gülşah Yavuz, Franck Verschuren, Christopher Ramos, Paule Denoel, Nicolas Wilmet, Michael Vandoorslaert, Alessandro Manara, Adeline Higuet, Amichai Sheffy, Sinan Kamona, Peter Jones, Mai Nguyen, Anne Clarke, Sierra Beck, Andrew Munro, Kim M. Yates, James Weaver, Deborah Moore, Stuart Innes, Karina Walters, Koen Simons, Anne‐Maree Kelly, Sharon Klim, Kerrie Russell, Anne‐Maree Kelly   +93 more
wiley   +1 more source

Review: Hormone Pregnancy Tests Were Teratogenic by the Same Failed Abortion and Hypoxia‐Related Mechanism as Misoprostol

Birth Defects Research, Volume 117, Issue 3, March 2025.
ABSTRACT Introduction Hormone pregnancy tests (HPTs), containing synthetic progesterone and oestrogen, were used to diagnose pregnancy in the 1950s to early 1980s. An existing pregnancy was purported to be unaffected while expulsion of the uterine lining (withdrawal bleed) was supposed to occur if the woman was not pregnant.
Bengt R. Danielsson, Helen E. Ritchie
wiley   +1 more source

Extracting Site Effects From P‐wave spectra: Application of Cluster‐Event Method 2 (CEM2) in the Tohoku Region, Japan

Journal of Geophysical Research: Solid Earth, Volume 130, Issue 1, January 2025.
Abstract Theories related to the Earth's attenuation effect and earthquake source properties predict a similar spectral falloff of body waves, creating severe trade‐off problems when determining these two processes from waveform spectra. Previous efforts attempted to suppress this trade‐off by either applying an empirical Green's function or conducting
Pei‐Ru Jian, Ban‐Yuan Kuo
wiley   +1 more source

Development of a Refined Model for a Rapid Compression and Expansion Machine with Pre-Chamber Applied to Study the Effects of Pre-Chamber Geometry and Hydrogen Enrichment on Combustion and Extinction of Methane/Air Flames

Energies
In this paper, experimental and numerical analyses are performed with a Rapid Compression and Expansion Machine (RCEM) equipped with a passive pre-chamber (PC) and fueled with premixed stoichiometric air/methane mixture to replicate engine-like ...
Fabio Bozza, Luigi Teodosio, Emanuele Ugliano, Ratnak Sok, Enrica Malfi, Jin Kusaka   +5 more
doaj   +1 more source

Prenatal findings in 11 cases with craniofacial microsomia using the Alberta Congenital Anomalies Surveillance System, 1997–2019

American Journal of Medical Genetics Part A, Volume 194, Issue 8, August 2024.
Abstract Craniofacial microsomia (CFM) primarily includes specific head and neck anomalies that co‐occur more frequently than expected. The anomalies are usually asymmetric and affect craniofacial features; however, there are frequently additional anomalies of variable severity. Published prenatal findings for CFM are limited. This study contributes 11
Mary Ann Thomas, Tanya Bedard, Susan Crawford, R. Brian Lowry   +3 more
wiley   +1 more source

Airway management in patients with suspected or confirmed cervical spine injury

Anaesthesia, Volume 79, Issue 8, Page 856-868, August 2024.
Summary Background There are concerns that airway management in patients with suspected or confirmed cervical spine injury may exacerbate an existing neurological deficit, cause a new spinal cord injury or be hazardous due to precautions to avoid neurological injury.
Matthew D. Wiles, Helen A. Iliff, Katherine Brooks, Egidio J. Da Silva, Mike Donnellon, Adrian Gardner, Matthew Harris, Caroline Leech, Steve Mathieu, Paul Moor, Lara Prisco, Kate Rivett, Frances Tait, Kariem El‐Boghdadly   +13 more
wiley   +1 more source

Doctors', Patients' and Physician Associates' Perceptions of the Physician Associate Role in the Emergency Department

Health Expectations, Volume 27, Issue 4, August 2024.
Abstract Introduction The Emergency Department (ED) has seen increased patient attendance and difficulty meeting demands. New healthcare professions such as Physician Associates (PAs) are being utilised to complement the existing medical workforce. Despite the growth of their professions in the United Kingdom, little evidence is available about the ...
Nicole M. A. King, Suzannah Helps, Yee Gan Ong, Sandra Walker   +3 more
wiley   +1 more source