Results 101 to 110 of about 192,491 (208)

Calcium Dynamics of Ganglion Cell Layer Neurons in rd1 Mice

, 2020
In the rd1 mouse model of inherited retinal degeneration, activation of P2X7 purinoreceptors (P2X7r) has been suggested to lead to the formation of pores permeable to large molecules in retinal ganglion cells (RGCs).
Carr, Jessica
core  

rd1 Mouse retina shows an imbalance in the activity of cysteine protease cathepsins and their endogenous inhibitor cystatin C.

, 2008
PURPOSE: To compare in vivo levels, spatial localization, and in vitro secretion of cysteine protease cathepsins and cystatin C (cysC) in the retinal degeneration 1 (rd1) mouse model of retinitis pigmentosa and control (wt) mouse retinas.
Ahuja, Sat pal, Ekström, Per, Ahuja Jensen, Poonam, Abrahamson, Magnus, Johnson, Leif, van Veen, Theo, Caffé, Romeo   +6 more
core   +1 more source

FAM20C directly binds to and phosphorylates Periostin. [PDF]

Sci Rep, 2020
Lin JH, Lin IP, Ohyama Y, Mochida H, Kudo A, Kaku M, Mochida Y.   +6 more
europepmc   +1 more source

Setaria cervi (Filarioidea, Onchocercidae) undressing in ungulates: altered morphology of developmental stages, their molecular detection and complete sequence cox1 gene. [PDF]

Parasitology, 2021
Lanková S, Vejl P, Melounová M, Čílová D, Vadlejch J, Miklisová D, Jankovská I, Langrová I.   +7 more
europepmc   +1 more source

Intravitreous injection of PLGA microspheres encapsulating GDNF promotes the survival of photoreceptors in the rd1/rd1 mouse.

, 2005
International audiencePURPOSE: To evaluate the potential delay of the retinal degeneration in rd1/rd1 mice using recombinant human glial cell line-derived neurotrophic factor (rhGDNF) encapsulated in poly(D,L-lactide-co-glycolide) (PLGA) microspheres ...
Halhal, Mounia, Andrieu-Soler, Charlotte, Aubert-Pouëssel, Anne, Doat, Marc, Venier-Julienne, Marie-Claire, Picaud, Serge, Benoit, Jean-Pierre, Behar-Cohen, Francine, Simonutti, Manuel   +8 more
core  

Detection of 5hmC during photoreceptor degeneration in the rd1 mouse.

, 2013
(A–E) Rd1 or (F–J) wild-type mouse retinas, P9 through P13, were labeled with antibodies against 5hmC (A–J). White arrows indicate 5hmC (+) cells in the ONL, dark arrows indicate occasional (+) cells in the INL.
Shannath L. Merbs (179936), Raymond A. Enke (198910), Donald J. Zack (9715), John A. Fuller (482087), Karl J. Wahlin (482086), Giedrius Kalesnykas (482088)   +5 more
core   +1 more source

Differential alterations in the expression of neurotransmitter receptors in inner retina following loss of photoreceptors in rd1 mouse.

, 2015
Loss of photoreceptors leads to significant remodeling in inner retina of rd1 mouse, a widely used model of retinal degeneration. Several morphological and physiological alterations occur in the second- and third-order retinal neurons.
Ipsit Srivastava, Prerna Srivastava, Abhinaba Ghosh, Narender K Dhingra, Sumit K Sinha-Mahapatra   +4 more
core   +1 more source

Tissue inhibitor of metalloproteinases 1 enhances rod survival in the rd1 mouse retina.

, 2018
Retinitis pigmentosa (RP), an inherited retinal degenerative disease, is characterized by a progressive loss of rod photoreceptors followed by loss of cone photoreceptors.
Andrew Vargas, Yun Sung Eom, Eun-Jin Lee, Justin Li, Cheryl Mae Craft (3179256), Hwa Sun Kim (3366581), Kyra L. Yamamoto (5194673), Justin Li (5194676), Eun-Jin Lee (2299186), Cheryl Mae Craft, Kyra L Yamamoto, Kyra L. Yamamoto, Yun Sung Eom (3179274), Hwa Sun Kim, Andrew Vargas (3366578)   +14 more
core   +1 more source

Surgical vs. nonoperative treatment for acute Achilles' tendon rupture: a meta-analysis of randomized controlled trials

Frontiers in Surgery
BackgroundAcute Achilles tendon rupture (AATR) is common among young individuals. There are various management options available, including conservative treatment, open surgical repair, and minimally invasive treatments.
Lei Fan, Yunan Hu, Leng Zhou, Weili Fu
doaj   +1 more source

Silicone as a smart solution for simulating soft tissue—an iterative approach to developing a high-fidelity sustainable training model for laparoscopic appendectomy

Frontiers in Surgery
BackgroundLaparoscopic appendectomy (LA) is an effective treatment for the surgical care of appendicitis, with this minimally invasive approach allowing patients to typically spend less time in hospital and promptly return to normal life activities ...
Adam F. Roche, Gabrielle Diebold, Niamh McCawley, William P. Duggan, Andrea J. Doyle, Tim Lawler, Caoimhin O’Conghaile, Claire M. Condron   +7 more
doaj   +1 more source