Results 131 to 140 of about 151,952 (148)

Alleviation of Photoreceptor Degeneration Based on Fullerenols in rd1 Mice by Reversing Mitochondrial Dysfunction via Modulation of Mitochondrial DNA Transcription and Leakage.

Small, 2023
Poor therapeutic outcomes of antioxidants in ophthalmologic clinical applications, including glutathione during photoreceptor degeneration in retinitis pigmentosa (RP), are caused by limited anti-oxidative capacity.
Junling Yang, Xia Chen, Luodan A, Hui Gao, Maoru Zhao, Lingling Ge, Minghui Li, Cao Yang, Yu-zhu Gong, Zhanjun Gu, Hai-Huang Xu   +10 more
semanticscholar   +1 more source

On The Efficacy of Cobalt Boride Coating on NMC-811 Cathode Under Vinylene Carbonate Additive, High Temperature and Air Shelving Conditions

Journal of the Electrochemical Society, 2023
Cobalt boride (CoB) is a novel coating material for high-voltage cathodes, which has demonstrated excellent protective capabilities for the NMC-811 cathode in the LiPF6-EC-EMC electrolyte.
Y. Jing, Y. Shao, H. Xin
semanticscholar   +1 more source

Expression of exogenous PDE5 rescues photoreceptors in rd1 mice.

Current Medicinal Chemistry, 2022
BACKGROUND Catalytic hydrolysis of cyclic guanosine monophosphate (cGMP) by phosphodiesterase 6 (PDE6) is a critical step in phototransduction signalling in photoreceptors.
Tongdan Zou, Ting Wang, Fangyuan Zhen, Xu He, Shuqian Dong, Houbin Zhang   +5 more
semanticscholar   +1 more source

Pembrolizumab plus trastuzumab and chemotherapy for HER2+ metastatic gastric or gastroesophageal junction (G/GEJ) cancer: Initial findings of the global phase 3 KEYNOTE-811 study.

Journal of Clinical Oncology, 2021
4013 Background: Trastuzumab (tras) plus chemotherapy (chemo) is standard-of-care (SOC) 1L therapy for HER2+ metastatic G/GEJ cancer. In two phase 2 studies, tras, chemo, and pembrolizumab (pembro) in combination showed promising efficacy and manageable ...
Y. Janjigian, A. Kawazoe, P. Yanez, S. Luo, S. Lonardi, O. Kolesnik, O. Barajas, Y. Bai, L. Shen, Yong Tang, L. Wyrwicz, K. Shitara, S. Qin, E. Cutsem, J. Tabernero, Lie Li, C. Shih, P. Bhagia, H. Chung   +18 more
semanticscholar   +1 more source

Bipolar redox electrolyte-synergistically mediated NiCoMn-811 high-Ni ternary perovskite fluorides for advanced supercapacitors in both alkaline and neutral media

, 2021
Perovskite fluorides (ABF3) as novel electrode materials have drawn particular attention for supercapacitors (SCs). However, the key issues to enhance energy storage capability, clarify charge storage mechanisms, employ different electrolytes media, and ...
Wei Shi, Wujiang Yu, R. Ding, Ziyang Jia, Yi Li, Yuxi Huang, Caini Tan, Xiujuan Sun, E. Liu   +8 more
semanticscholar   +1 more source

Health-related quality of life (HRQOL) with pembrolizumab (pembro) plus trastuzumab (tras) and chemotherapy (chemo) in first-line HER2-positive (HER2+) advanced gastric cancer: KEYNOTE-811 trial results.

Journal of Clinical Oncology
286 Background: In the phase 3 KEYNOTE-811 study (NCT03615326), first-line (1L) pembro with tras + chemo (pembro arm) yielded superior PFS and improved ORR with durable responses versus placebo (pbo) with tras + chemo (pbo arm) in pts with HER2 ...
Y. Janjigian, A. Kawazoe, Jianming Xu, S. Lonardi, J. Metges, L. Wyrwicz, L. Shen, Y. Ostapenko, M. Bilici, M. Lowery, A. Valderrama, Y. Guan, Kan Li, C. Shih, S. Rha   +14 more
semanticscholar   +1 more source

Li-Nb-O coating/substitution enhances the electrochemical performance of LiNi0.8Mn0.1Co0.1O2 (NMC 811) Cathode.

ACS Applied Materials and Interfaces, 2019
High-nickel layered oxides, such as NMC 811, are very attractive high energy density cathode materials. However, the high nickel content creates a number of challenges, including high surface reactivity and structural instability. Through a wet chemistry
F. Xin, Hui-jie Zhou, Xiaobo Chen, M. Zuba, Natasha A. Chernova, Guangwen Zhou, M. Whittingham   +6 more
semanticscholar   +1 more source

Editors' Choice—Capacity Fading Mechanisms of NCM-811 Cathodes in Lithium-Ion Batteries Studied by X-ray Diffraction and Other Diagnostics

Journal of the Electrochemical Society, 2019
Ni-rich layered oxides, like NCM-811, are promising lithium-ion battery cathode materials for applications such as electric vehicles.
F. Friedrich, Benjamin Strehle, A. Freiberg, Karin Kleiner, S. Day, C. Erk, M. Piana, H. Gasteiger   +7 more
semanticscholar   +1 more source

Photoperiod integration in C3H rd1 mice

Journal of Pineal Research, 2020
In mammals, the suprachiasmatic nuclei (SCN) constitute the main circadian clock, receiving input from the retina which allows synchronization of endogenous biological rhythms with the daily light/dark cycle.
Bastien Leclercq, D. Hicks, V. Laurent
semanticscholar   +1 more source