Results 61 to 70 of about 192,491 (208)

Obstrucción intestinal parcial por invaginación en una paciente joven con antecedente de síndrome de Peutz-Jeghers

Revista Colombiana de Cirugía
El síndrome de Peutz-Jeghers (SPJ) es una entidad poco frecuente, con un patrón de herencia autosómica dominante, causado por la mutación del gen STK11, el cual codifica para una enzima proteína quinasa de serina/treonina que actúa como un supresor ...
Clara Briceño-Morales, Alejandra Castrillón-Gallego, Mariana Blanco-Betancur, Erika Fernanda Castro-Palencia   +3 more
doaj   +1 more source

Time course of cone loss in rd1Cx36^+/+ and rd1Cx36^−/− mice.

, 2013
Quantification of cones in vertical sections of the central retina (defined up to a distance of 1,000 µm from the optic nerve), as indicated in A. B–G show magnifications of the quantified regions in the central ONL of cone arrestin-labeled vertical ...
Karin Dedek (41152), François Paquet-Durand (214303), Ulrike Janssen-Bienhold (213416), Reto Weiler (41159), Katharina Kranz (383202)   +4 more
core   +1 more source

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus

Arthritis & Rheumatology, 2017
Interferon‐γ (IFNγ) is implicated in the pathogenesis of discoid lupus erythematosus (DLE). This study sought to evaluate a single dose of AMG 811, an anti‐IFNγ antibody, in patients with DLE.
V. Werth, D. Fiorentino, B. Sullivan, M. Boedigheimer, Kit Chiu, Christine Wang, G. E. Arnold, M. Damore, J. Bigler, A. Welcher, C. Russell, David A. Martin, James B. Chung   +12 more
semanticscholar   +1 more source

Both rd1 and MNU-injected mice had higher numbers of mRGCs, but only rd1 mice had a higher proportion of Brn3b-expressing M1 cells than in wild-type.

, 2016
A) Representative images from flatmounted retinas double-labeled for melanopsin (green) and Brn3b (red), showing non-M1 cells (arrows) in wild-type (WT, left), rd1 (middle) and MNU (7 days post injection; right). Top row shows original images, middle row
Manvi Goel (530287), Ipsit Srivastava (716736), Shriya Palchaudhuri (2832845), Varsha Jain (2832842), Narender K. Dhingra (530289), Sumit K. Sinha-Mahapatra (716734)   +5 more
core   +1 more source

Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration

Investigative Ophthalmology and Visual Science, 2018
Purpose As an active component in wolfberry, lycium barbarum polysaccharides (LBP) are capable of protecting retinal neurons in several animal disease models.
Feng Liu, Jia Zhang, Zongqin Xiang, Di Xu, K. So, N. Vardi, Ying Xu   +6 more
semanticscholar   +1 more source

Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?

, 2005
PURPOSE: We previously demonstrated that exogenous glial cell line-derived neurotrophic factor (GDNF) induces histological and functional protection of photoreceptors in the retinal degeneration (rd1) mouse model.
Neveux, N, Leveillard, T, Sahel, JA, Simonutti, M, Delyfer, MN   +4 more
core  

GABAcR-ρ2 levels were downregulated in rd1 mouse retina.

, 2015
A) Representative blots of GABAcR-ρ2 and β-tubulin in adult wild-type and rd1 mouse retinas. Black vertical line indicates that the two bands were not adjacent.
Abhinaba Ghosh (716735), Ipsit Srivastava (716736), Prerna Srivastava (716733), Narender K. Dhingra (530289), Sumit K. Sinha-Mahapatra (716734)   +4 more
core   +1 more source

Human melanopsin-AAV2/8 transfection to retina transiently restores visual function in rd1 mice [PDF]

, 2016
AIM: To explore whether ectopic expression of human melanopsin can effectively and safely restore visual function in rd1 mice. METHODS: Hematoxylin-eosin staining of retinal sections from rd1 mice was used to detect the thickness of the outer nuclear ...
Wen-Yi Liu, Ming-Ming Liu, Zheng-Qin Yin, Cong-Jian Zhao, Jia-Man Dai, Bin Lin   +5 more
core   +1 more source

Spatio-temporal characterization of S- and M/L-cone degeneration in the Rd1 mouse model of retinitis pigmentosa

BMC Neuroscience, 2019
The Pde6brd1 (Rd1) mouse is widely used as a murine model for human retinitis pigmentosa. Understanding the spatio-temporal patterns of cone degeneration is important for evaluating potential treatments.
Daniel S Narayan, J. Ao, J. Wood, R. Casson, G. Chidlow   +4 more
semanticscholar   +1 more source

Peripheral blood-derived monocytes show neuronal properties and integration in immune-deficient rd1 mouse model upon phenotypic differentiation and induction with retinal growth factors

Stem cell research & therapeutics, 2020
Background Cell therapy is one of the most promising therapeutic interventions for retinitis pigmentosa. In the current study, we aimed to assess if peripheral blood-derived monocytes which are highly abundant and accessible could be utilized as a ...
Alaknanda Mishra, K. V. Mohan, P. Nagarajan, S. Iyer, Ashwani Kesarwani, Madhu Nath, Laxmi Moksha, Jashdeep Bhattacharjee, Barun Das, K. Jain, P. Sahu, Prakriti Sinha, T. Velapandian, P. Upadhyay   +13 more
semanticscholar   +1 more source