Results 41 to 50 of about 62,487 (100)

The Use of Structurally Augmented 3D Printed Cages in Segmental Defects of the Tibial Shaft

Foot & Ankle Orthopaedics, 2019
Category: Trauma, Emerging Technology Introduction/Purpose: Modern day management of segmental defects of the tibia shaft (SDTS) involve autologous nonvascularized grafts, autologous vascularized contralateral fibula grafts, as well as bone transport ...
Joseph Tracey MSc, BSc(Med), Selene Parekh MD, MBA   +1 more
doaj   +1 more source

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus

Arthritis & Rheumatology, 2017
Interferon‐γ (IFNγ) is implicated in the pathogenesis of discoid lupus erythematosus (DLE). This study sought to evaluate a single dose of AMG 811, an anti‐IFNγ antibody, in patients with DLE.
V. Werth, D. Fiorentino, B. Sullivan, M. Boedigheimer, Kit Chiu, Christine Wang, G. E. Arnold, M. Damore, J. Bigler, A. Welcher, C. Russell, David A. Martin, J. Chung   +12 more
semanticscholar   +1 more source

A novel autologous-made matrix using hyaline cartilage chips and platelet-rich growth factors for the treatment of full-thickness cartilage or osteochondral defects: Preliminary results

Journal of Orthopaedic Surgery, 2019
Purpose: To report the clinical, functional, and magnetic resonance imaging (MRI)-based outcomes of a novel autologous-made matrix consisting of hyaline cartilage chips combined with mixed plasma poor rich in platelets clot and plasma rich in growth ...
Ramón Cugat, Eduard Alentorn-Geli, Jordi Navarro, Xavier Cuscó, Gilbert Steinbacher, Roberto Seijas, Pedro Álvarez-Díaz, David Barastegui, Patricia Laiz, Gonzalo Samitier, Montserrat García-Balletbó   +10 more
doaj   +1 more source

Massive Prepatellar Bursitis in Post-Polio Residual Paralysis: A Case Report

Journal of Orthopaedic Surgery, 2001
We report a case of post-polio residual paralysis, an eighteen-year old girl who was ambulatory on all four limbs and presented to us with a massive pre-patellar bursitis on her left knee.
Anil K Bhat, Kumar Bhaskaranand
doaj   +1 more source

Giant cell tumor of distal radius treated with ulnar translocation and wrist arthrodesis

Journal of Orthopaedic Surgery, 2017
Introduction: The aim is to analyze the functional outcomes of patients of giant cell tumor (GCT) of distal radius treated with ulnar translocation and wrist arthrodesis.
Abhijeet Ashok Salunke, Jaymin Shah, Vikas Warikoo, Amit Chakraborty, Harshwardhan Pokharkar, Yongsheng Chen, Manish Pruthi, Jyotindra Pandit   +7 more
doaj   +1 more source

Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis

Lupus Science and Medicine, 2017
Objective To evaluate safety, pharmacokinetics and pharmacodynamics of anti-interferon (IFN)-γ monoclonal antibody AMG 811 in subjects with SLE without or with lupus nephritis (LN).
Michael J Boedigheimer, David A. Martin, Zahir Amoura, J. Sánchez-Guerrero, J. Romero-Díaz, A. Kivitz, C. Aranow, Tak Mao Chan, Yip Boon Chong, Kit Chiu, Christine Wang, W. Sohn, G. E. Arnold, M. Damore, A. Welcher, Barbara A. Sullivan, Brian L. Kotzin, James B. Chung   +17 more
semanticscholar   +1 more source

Laminoplasty after Anterior Spinal Fusion for Cervical Spondylotic Myelopathy

Journal of Orthopaedic Surgery, 2009
Purpose. To review outcomes of laminoplasty after anterior spinal fusion (ASF) in 8 patients with cervical spondylotic myelopathy (CSM). Methods. Records of 3 men and 5 women aged 49 to 80 (mean, 60) years who underwent laminoplasty after ASF for CSM ...
Chun-Hong Pang, Hon-Bong Leung, Chi-Hung Yen   +2 more
doaj   +1 more source

Unipolar versus Bipolar Uncemented Hemiarthroplasty for Elderly Patients with Displaced Intracapsular Femoral Neck Fractures

Journal of Orthopaedic Surgery, 2011
Purpose. To compare outcomes of unipolar versus bipolar uncemented hemiarthroplasty and determine factors affecting outcomes. Methods. 433 and 274 elderly patients with displaced intracapsular femoral neck fractures underwent uncemented unipolar ...
Bhushan M Sabnis, Ivan J Brenkel
doaj   +1 more source

Simultaneous Dislocation of Proximal and Distal Radio-Ulnar Joints: A Case Report

Journal of Orthopaedic Surgery, 2013
Simultaneous dislocation of the radial head and distal radio-ulnar joint is rare. We report a 71-year-old man with volar dislocation of the radial head and dorsal dislocation of the distal radio-ulnar joint, and discuss the injury mechanism and its ...
Billy LK Wong, Krishna Boddu Siva Rama, Ajeet Kumar   +2 more
doaj   +1 more source

PAN-811 prevents chemotherapy-induced cognitive impairment and preserves neurogenesis in the hippocampus of adult rats

PLoS ONE, 2018
Chemotherapy-induced cognitive impairment (CICI) occurs in a substantial proportion of treated cancer patients, with no drug currently available for its therapy.
Zhi-Gang Jiang, G. Winocur, J. Wojtowicz, O. Shevtsova, S. Fuller, H. Ghanbari   +5 more
semanticscholar   +1 more source