Results 251 to 260 of about 126,234 (299)

Expression of rDNA insertions during rDNA magnification in D. melanogaster

Molecular and General Genetics MGG, 1983
In D. melanogaster, many ribosomal genes contain an intervening sequence that interrupts the 28S rRNA gene. In wild-type flies, type I and type II insertions are rarely transcribed and the transcripts of the interrupted genetic units do not contribute significantly to the production of mature ribosomal RNA. We demonstrate that during rDNA magnification,
T, Labella, L, Vicari, A, Manzi, F, Graziani   +3 more
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Evidence for an excess of rDNA in the testis ofDrosophila melanogaster during rDNA magnification

Molecular and General Genetics MGG, 1977
Hybridization of rRNA and DNA extracted from different tissues of different genotypes have been performed. The results show that: 1) in DNA extracted from the testis of premagnified males there exists an excess of rDNA, which is consistent with the model proposed by Ritossa (1972) and by us (1973) to explain the phenomenon of magnification.
D, Locker, M, Marrakechi
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Amplification of rDNA and type I sequences in Drosophila males deficient in rDNA

Cell, 1983
rDNA magnification is a heritable change in rDNA content that occurs in D. melanogaster males when chromosomes deficient in rDNA are placed together for several generations. We have examined the restriction endonuclease cleavage pattern of the rDNA from an X chromosome undergoing magnification, and find no evidence for the selective amplification of ...
D V, de Cicco, D M, Glover
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Regulation of rDNA stability by sumoylation

DNA Repair, 2009
Repair of DNA lesions by homologous recombination relies on the copying of genetic information from an intact homologous sequence. However, many eukaryotic genomes contain repetitive sequences such as the ribosomal gene locus (rDNA), which poses a risk for illegitimate recombination.
Eckert-Boulet, Nadine, Lisby, Michael
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Chromosomal localization of rDNA in the gorilla

Cytogenetic and Genome Research, 1998
Twenty-five specimens of lowland gorilla, including 24 specimens of the western lowland gorilla <i>(Gorilla gorilla gorilla) </i>and 1 specimen of the eastern lowland gorilla<i> (G. gorilla graueri), </i>were investigated by fluorescence in situ hybridization with a human-derived 18S + 28S rDNA probe.
W, Schempp, S, Zeitler, W, Rietschel
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rDNA transcription and cardiac hypertrophy

Trends in Cardiovascular Medicine, 1993
A common result of the various stimuli that alter the growth rates of cells is a parallel alteration of the rate of ribosome biogenesis. In many cell types, this mandates an altered rate of ribosomal RNA synthesis. Preliminary studies indicate that rDNA transcription may in fact be regulated at more than one level or step.
W, Xie, L I, Rothblum
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Immunogenicity of rDNA-derived pharmaceuticals

Trends in Pharmacological Sciences, 2002
Many biopharmaceuticals have been reported to induce the production of antibodies. Several factors influence immunogenicity, including the methods of production, formulation and storage as well as patient characteristics (e.g. type of disease and genetic background).
Ryff, J.C., Schellekens, H.
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Initiation of transcription of rDNA in rice

Biochemical and Biophysical Research Communications, 1989
Three direct repeats of 320, 340 and 238 nucleotides were detected upstream to the 5' end of the 18S rRNA gene of an rDNA unit present on a 9.8 kb EcoRI fragment of the rice DNA. The primer extension analysis showed that the site of initiation of transcription is in the 1st repeat at an A, the 623rd nucleotide upstream to the 5' end of the 18S rRNA ...
Nandabalan, K, Padayatty, JD
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Chromosomal localization of rDNA in the Brassicaceae

Genome, 2005
A survey is given about the number and chromosomal position of rDNA loci in 45 Brassicaceae species. For 34 species, 5S and 45S rDNA loci have been localized by two-colour fluorescence in situ hybridization for the first time. These data show the variability of rDNA within karyotypes of the Brassicaceae, provide anchor points for (comparative) genetic
Hoda B M, Ali, Martin A, Lysak, Ingo, Schubert   +2 more
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The study of a rDNA replicator in Saccharomyces

Current Genetics, 1983
We have previously demonstrated that the loss of Rcp-CEN3, a centromeric plasmid containing yeast rDNA autonomously replicating sequences (ARS) is as high as around 50% per generation for most yeast strains. In this study we have attempted to elucidate mechanisms underlying the high mitotic instability of Rcp-CEN3. For this purpose a tandem duplication
N Y, Kouprina, V L, Larionov
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