Results 101 to 110 of about 6,587 (198)
Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm
British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley +1 more source
In what sense are mental disorders brain disorders? Explicating the concept of mental disorder within RDoC [PDF]
, 2020 Recently there has been a trend of moving towards biological and neurocognitive based classifications of mental disorders that is motivated by a dissatisfaction with the syndrome-based classifications of mental disorders.
Malatesti, Luca +2 more
core +1 more source
Transdiagnostic Biomarkers of Psychopathology: A Conceptual Review
Early Intervention in Psychiatry, Volume 20, Issue 10, October 2026.ABSTRACT Introduction Psychiatric biomarker research has traditionally been organized around diagnostic categories, but clinical heterogeneity, comorbidity and shared biological mechanisms across psychiatric conditions have increased interest in transdiagnostic approaches.
Katelyn Hummel +4 more
wiley +1 more source
Solar RRL, Volume 10, Issue 17, 15 September 2026.All‐polymer PM6:PY‐IT solar cells processed by blade coating in air using o‐xylene are studied alongside a PM6:Y12 binary reference and an advanced ternary PM6:Y12:PY‐IT system. We examine electron transport layers and additives to tune morphology, charge transport, and device efficiency. Characterization includes J–V, GIWAXS, AFM, and SCLC.
Mohamed el A. Kramdi +8 more
wiley +1 more source
Basic Science, RDoC, and Schizophrenia Bulletin [PDF]
Schizophrenia Bulletin, 2014 Since assuming operation of Schizophrenia Bulletin in 2005, the current editorial office has endeavored to increase the journal’s presence in publishing basic neuroscience research relating to schizophrenia. In the 5year period preceding the journal’s transition from the National Institutes of Health (NIH) to a consortium operated jointly by the ...
openaire +1 more source
O projeto Research Domain Criteria e o abandono da tradição psicopatológica
Revista Latinoamericana de Psicopatologia Fundamental, 2014 O artigo explora os pressupostos epistemológicos do Research Domain Criteria (RDoC) - projeto de investigação empírica dos transtornos mentais, dentro de uma plataforma biológica - promovido pelo National Institute of Mental Health (NIMH).
Rafaela Zorzanelli +2 more
doaj +1 more source
European PsychiatryIntroduction Recently there have been increased acceptance of complementary and alternative medicine (including traditional medicines) not only among laypersons but also various medical specialities.
W. Upadhyaya, A. Iyer
doaj +1 more source
The Role of Chronic Stress in Anxious Depression
Chronic Stress, 2017 Depression is a heterogeneous disease with many different subtypes. Patients with the anxious depression—a common subtype of major depression—are at an increased risk for treatment-resistance to standard antidepressants, with resultant increases in ...
Rachel A. Ross +2 more
doaj +1 more source