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Psychophysiology, 2016
AbstractAs highlighted by articles in the current special issue, the RDoC initiative holds promise for advancing understanding of mental health problems. However, the initiative is at its early stages and it remains unclear what level of progress can be achieved and how quickly.
Greg Hajcak, Christopher Patrick
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Research Domain Criteria (RDoC): Progress and Potential

Current Directions in Psychological Science, 2022
The National Institute of Mental Health (NIMH) addressed in its 2008 Strategic Plan an emerging concern that the current diagnostic system was hampering translational research, as accumulating data suggested that the system’s disorder categories constituted heterogeneous syndromes rather than specific diseases.
Bruce Cuthbert
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The RDoC initiative and the structure of psychopathology

Psychophysiology, 2016
AbstractThe NIMH Research Domain Criteria (RDoC) project represents a welcome effort to circumvent the limitations of psychiatric categories as phenotypes for psychopathology research. Here, we describe the hierarchical and dimensional structure of phenotypic psychopathology and illustrate how this structure provides phenotypes suitable for RDoC ...
Robert F, Krueger, Colin G, DeYoung
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Psychophysiology as a core strategy in RDoC

Psychophysiology, 2016
AbstractThe Research Domain Criteria (RDoC) initiative of the National Institute of Mental Health shows great promise in providing guidance for research on mental illness but has prompted considerable controversy. Papers by Yancey, Venables, and Patrick and Kozak and Cuthbert illustrate and clarify a number of important features of RDoC.
Gregory A, Miller +3 more
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Implications of RDoC for the Research and Practice of Psychotherapy

Behavior Therapy, 2015
The field of psychotherapy is at an important juncture. Recent changes in the field include (a) the skeptical reception of the fifth edition of the Diagnostic and Statistical Manual and (b) NIMH's prioritization of an alternative classification system to guide translational and intervention research.
Rachel, Hershenberg, Marvin R, Goldfried
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Psychopathic traits from an RDoC perspective

Current Opinion in Neurobiology, 2015
In this review an RDoC approach is applied to psychopathic traits. Two core neuro-cognitive systems relevant to the emergence of psychopathic traits are considered. These are the response to other individuals' emotional displays and reinforcement-based decision-making.
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RDoC’s Metaphysical Assumptions: Problems and Promises

2017
Critics contend that the categories within the DSM are fueling the current crisis in psychiatry because they are not valid. As a remedy, NIMH has established RDoC, a framework of psychological and behavioral constructs that will — they believe — better guide the search for the biological mechanisms of psychopathology.
Ginger A. Hoffman, Peter Zachar
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PTSD, Endophenotypes, the RDoC, and the DSM-5

Psychological Injury and Law, 2014
The search for endophenotypes that stand between genetics and disease has been applied to the diagnostic entity of Posttraumatic Stress Disorder (PTSD). Advances are being made in understanding the pathway to disorder in PTSD in terms of brain regions, neuronal networks, stress-related systems (e.g., the hypothalamic–pituitary–adrenal (HPA) axis), and ...
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