Results 41 to 50 of about 6,180 (198)

Understanding Suicide Risk Within the Research Domain Criteria (RDoC) Framework: Insights, Challenges, and Future Research Considerations [PDF]

, 2018
Suicide is a leading cause of death worldwide. Prior research has focused primarily on sociodemographic and psychiatric risk factors with little improvement in the prediction or prevention of suicidal behavior over time.
Nock, Matthew, Cha, Christine, Glenn, Catherine R., Kleiman, Evan   +3 more
core   +1 more source

Taking an RDoC lens to the study of panic disorder: A commentary on Hamm et al. and other thoughts on RDoC [PDF]

Psychophysiology, 2016
AbstractThe Research Domain Criteria (RDoC) initiative put forth by the National Institute of Mental Health represents an exciting new framework in which to study psychopathology. The article by Hamm et al. (2016) is an interesting application of an “RDoC lens” toward a program of research on panic disorder.
Stewart A, Shankman, Andrea C, Katz, Scott A, Langenecker   +2 more
openaire   +2 more sources

Psychoeducation Tensor as Cognitive Architecture for RDoC

, 2023
This is a companion poster for the preprint article entitled "Psychoeducation Tensor Framework as a Cognitive Architecture for the Research Domain Criteria (RDoC) Framework." Article Abstract: The psychoeducation tensor (PET) framework integrates a ...
Joseph Zalman Sheppard
core   +1 more source

RDoC and DSM-5: What's the Fuss? [PDF]

Schizophrenia Bulletin, 2013
Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) is easy to criticize, and most criticisms would apply to DSM-IV, III, or any versions of the International Classification of Diseases (ICD). The central dissatisfaction is with the creation of a large number of specific diagnostic classes that continue to define clinical ...
openaire   +2 more sources

Endocannabinoid signaling in social functioning: an RDoC perspective [PDF]

Translational Psychiatry, 2016
AbstractCore deficits in social functioning are associated with various neuropsychiatric and neurodevelopmental disorders, yet biomarker identification and the development of effective pharmacological interventions has been limited. Recent data suggest the intriguing possibility that endogenous cannabinoids, a class of lipid neuromodulators generally ...
Karhson, D S, Hardan, A Y, Parker, K J
openaire   +2 more sources

Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene

Disease Models & Mechanisms, 2017
The research domain criteria (RDoC) matrix has been developed to reorient psychiatric research towards measurable behavioral dimensions and underlying mechanisms.
Valentina Vengeliene, Anton Bespalov, Martin Roßmanith, Sandra Horschitz, Stefan Berger, Ana L. Relo, Hamid R. Noori, Peggy Schneider, Thomas Enkel, Dusan Bartsch, Miriam Schneider, Berthold Behl, Anita C. Hansson, Patrick Schloss, Rainer Spanagel   +14 more
doaj   +1 more source

Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri, Alessandro Serretti, Marco Menchetti, Benedetta Vai, Francesco Benedetti, Lidia Fortaner‐Uyà, Concetta Crisafulli   +6 more
wiley   +1 more source

Psilocybin as a Transdiagnostic Treatment for Eating Disorders and Comorbid Psychopathology: Implications for Clinical Nosology and Research Directions

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) are characterized by high rates of psychiatric comorbidity and suboptimal treatment outcomes. There remain critical gaps in research, including the exploration of effective transdiagnostic interventions. This forum article examines the potential of psilocybin treatment (PT) as a transdiagnostic intervention for
Elena Koning, Jérémie Richard, Aaron Keshen   +2 more
wiley   +1 more source

In what sense are mental disorders brain disorders? Explicating the concept of mental disorder within RDoC [PDF]

, 2020
Recently there has been a trend of moving towards biological and neurocognitive based classifications of mental disorders that is motivated by a dissatisfaction with the syndrome-based classifications of mental disorders.
Malatesti, Luca, Jurjako, Marko, Juriako, Marko   +2 more
core   +1 more source

A synthesis of evidence on inhibitory control and auditory hallucinations based on the Research Domain Criteria (RDoC) framework.

Frontiers in Human Neuroscience, 2014
The National Institute of Mental Health initiative called the Research Domain Criteria (RDoC) project aims to provide a new approach to understanding mental illness grounded in the fundamental domains of human behaviour and psychological functioning.
Johanna C. Badcock, Johanna C. Badcock, Kenneth eHugdahl   +2 more
doaj   +1 more source