Results 111 to 120 of about 618,204 (291)

Coaching the coaches: exploring the effectiveness of the ‘Move Well Be strong’ youth injury prevention programme for grassroot coaches and PE teachers

Annals of Medicine
Introduction Coaches play a major role in developing movement in their performers, especially at grassroots levels. However, there are significant knowledge gaps amongst grassroots coaches and physical education (PE) teachers regarding movement ...
J. D. Hughes, F. Ayala, W. M. Roberts, K. Wing, M. B. A. De Ste Croix   +4 more
doaj   +1 more source

Kids Out; evaluation of a brief multimodal cluster randomized intervention integrated in health education lessons to increase physical activity and reduce sedentary behavior among eighth graders

BMC Public Health, 2019
Background Most Finnish adolescents are not sufficiently physically active. Health education (HE) provides beneficial starting point for physical activity (PA) promotion in schools. This study evaluates an intervention integrated into three HE lessons to
M. Aittasalo, A-M Jussila, K. Tokola, H. Sievänen, H. Vähä-Ypyä, T. Vasankari   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Diffusion of excellence: evaluating a system to identify, replicate, and spread promising innovative practices across the Veterans health administration

Frontiers in Health Services
IntroductionThe Veterans Health Administration (VHA) Diffusion of Excellence (DoE) program provides a system to identify, replicate, and spread promising practices across the largest integrated healthcare system in the United States.
George L. Jackson, George L. Jackson, Gemmae M. Fix, Gemmae M. Fix, Gemmae M. Fix, Brandolyn S. White, Sarah L. Cutrona, Sarah L. Cutrona, Caitlin M. Reardon, Laura J. Damschroder, Madison Burns, Kathryn DeLaughter, Marilla A. Opra Widerquist, Maria Arasim, Jennifer Lindquist, Allen L. Gifford, Allen L. Gifford, Allen L. Gifford, Heather A. King, Heather A. King, Heather A. King, Jenesse Kaitz, Guneet K. Jasuja, Guneet K. Jasuja, Guneet K. Jasuja, Timothy P. Hogan, Timothy P. Hogan, Jaifred Christian F. Lopez, Jaifred Christian F. Lopez, Blake Henderson, Blaine A. Fitzgerald, Amber Goetschius, Danielle Hagan, Carl McCoy, Alex Seelig, Andrea Nevedal   +35 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Implementation of remote home care: assessment guided by the RE-AIM framework

BMC Health Services Research
Abstract Background Welfare technology interventions have become increasingly important in home-based palliative care for facilitating safe, time-efficient, and cost-effective methods to support patients living independently. However, studies evaluating the implementation of welfare technology innovations are scarce, and
Oelschlägel, Lina, Moen, Anne, Dihle, Alfhild, Christensen, Vivi L., Heggdal, Kristin, Österlind, Jane, Steindal, Simen A.   +6 more
openaire   +8 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Two-year scale-up dissemination study of a multi-strategic community-wide intervention promoting physical activity: a single-arm pre-post hybrid effectiveness-implementation trial

International Journal of Behavioral Nutrition and Physical Activity
Background Intervention trials that have demonstrated significant effects may not always replicate those effects when scaled up. This study aimed to test whether scaling-up a successful cluster randomized trial (the COMMUNICATE study, 9 intervention ...
Aoi Tsuzuki, Masamitsu Kamada, Shiho Amagasa, Jun Kitayuguchi, Takuma Miyashita, Takafumi Abe, Tatsunosuke Gomi, Kenta Okuyama, Masataka Taguri, Shigeru Inoue   +9 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source