Results 211 to 220 of about 632,564 (234)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Barriers and facilitators of implementing a community workshop series to mitigate maternal-child food insecurity: a mixed-methods RE-AIM evaluation. [PDF]

BMC Public Health
Herlosky K, Leverett A, Philbert R', Hernandez C, McDonough M, Nematian E, Mancha K, Jenkins R, Simpson J, Kyle C, Henry T, Ross V, Simangan D, Poblacion A, Baumann A, Buccini G.   +15 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A feasibility study using the RE-AIM framework: healthcare providers' and community partners' perceptions of a psychosocial intervention for Latino patient-caregiver dyads coping with advanced cancer. [PDF]

BMC Health Serv Res
Torres-Blasco N, Torres-Marrero SD, De Lahongrais-Lamboy A, Rivera-Torres N, Rosario-Ramos L, Argüelles-Berrios C.   +5 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Improving the usability of online resources to support implementation research and practice: The RE-AIM website use case. [PDF]

J Clin Transl Sci
Pereira EL, Strayer TE, Harden SM, Glasgow RE, Studts C, Estabrooks PA, Huebschmann AG.   +6 more
europepmc   +1 more source

Exploring the Integration of Consumer Activity Trackers Into a Community Weight Management Intervention to Support Physical Activity in Adults at Risk for or With Type 2 Diabetes: Mixed Methods Study Using the RE-AIM Framework. [PDF]

JMIR Diabetes
Hodgson W, Kirk A, Lennon M, Janssen X, Kennedy D.   +4 more
europepmc   +1 more source