Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Commentary: Expanding the horizons of RE-AIM framework in public health research
Türkiye Halk Sağlığı DergisiObjective: This commentary critically examines Yuliawati et al.’s 2024 review, “Analysis of research public health trends with the RE-AIM model and VOSviewer: A literature review,” which investigates the application of the “Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM)” framework in public health research.
openaire +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Implementing Culturally Tailored Diabetes Prevention in Hispanic Communities: An Integrative Review Using the RE-AIM Framework. [PDF]
Prev Chronic DisNguyen R.
europepmc +1 more source
Examining an Australian physical activity and nutrition intervention useing RE-AIM
, 2015 Introduction - Translating evidence-based interventions into community practice is vital to health promotion. This study used the RE-AIM framework to evaluate the larger dissemination of the ManUp intervention, an intervention which utilized interactive ...
Corneel Vandelanotte (9841796) +8 more
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Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
SUBVERSIVE FLORI.CULTURES. Ecological manoeuvres from the re-existing South
, 2017 The article deals with the need to approach a decolonial critique of the notion of nature, both in its theoretical and methodological dimension, since it has been clearly reified by Western scientific knowledge to sustain inequalities of power or the ...
Romero Caballero, Belén
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