Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women
Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea +10 more
wiley +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
ABSTRACT During their long evolutionary history, land plants have evolved a range of adaptations to different abiotic stressors. These help explain present‐day diversity and distribution patterns, as well as the potential resilience of natural and agricultural systems to a changing climate. Most previous research has focused on adaptation to individual
Marc Fradera‐Soler +6 more
wiley +1 more source
ABSTRACT Chief executive officers (CEOs) play a pivotal role in shaping public discourse on climate change through social media, yet how their language use affects the effectiveness of climate‐related posts remains unclear. Drawing on schema‐congruity theory and leader role expectations, we conceptualize certainty in language as congruent and anxiety ...
Ellen Weber +4 more
wiley +1 more source
Prolonged <sup>187</sup>Os/<sup>188</sup>Os excursion implies hydrothermal influence after the Chicxulub impact in the Gulf of Mexico. [PDF]
Sato H +9 more
europepmc +1 more source
Durable Fuel Cell Cathode Enabled by Pt Embedded Nanoscale Carbon Network via a Scalable Process
Platinum nanoparticles embedded nanoscale carbon network (Pt‐e‐Cn) are developed via a scalable flame spray pyrolysis process. Proton exchange membrane fuel cells (PEMFC) employing mesoporous Pt‐e‐Cn cathode electrocatalysts exhibit exceptional durability without compromising performance.
Suriya Venkatesan +10 more
wiley +1 more source
Evaluating the Use and Feasibility of Indocyanine Green (ICG) as a Beacon of Precision in Sentinel Node Biopsy for Breast Cancer from an Oncoplastic Practice in India. [PDF]
Koppiker CB +13 more
europepmc +1 more source
Replacing the oxygen evolution reaction with the electro‐oxidation of pollutants and waste streams offers an energy‐efficient route for simultaneous hydrogen production and pollutant remediation. This review summarizes the reaction mechanisms, catalyst design principles, and emerging paired‐electrolysis strategies that govern activity, selectivity ...
Safa Al‐Yahyaey +4 more
wiley +1 more source
Physeal breach as a potential predictor of pulmonary metastasis in paediatric osteosarcoma. [PDF]
Lin Z +6 more
europepmc +1 more source
On Metal Carbonyl Compounds in Catalytic Methanol Synthesis: Detection, Consequences, and Removal
Deactivation of Cu/ZnO/Al2O3 catalysts by metal carbonyl compounds in the feed gas is a critical problem in catalytic methanol synthesis. We utilize PTR–MS to identify potential chemical sources, detect contamination in an in‐house CO gas line, and validate filter methods for removing these catalyst poisons before synthesis.
Florian Stappert +4 more
wiley +1 more source

