Results 231 to 240 of about 11,607 (279)

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Unveiling a new oceanic anoxic event at the Norian/Rhaetian boundary (Late Triassic). [PDF]

Sci Rep
Rigo M, Jin X, Godfrey L, Katz ME, Sato H, Tomimatsu Y, Zaffani M, Maron M, Satolli S, Concheri G, Cardinali A, Wu Q, Du Y, Lei JZX, van Wieren CS, Tackett LS, Campbell H, Bertinelli A, Onoue T.   +18 more
europepmc   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

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Re-Os isotopic dating of molybdenites in the Xiaoliugou W (Mo) deposit in the northern Qilian mountains and its geological significance

Geochimica et Cosmochimica Acta, 1999
Abstract The Xiaoliugou is a large-scale W (Mo) deposit newly explored in the Northern Qilian Mountains Caledonian fold belt, Northwestern China. It is a vein and skarn type deposit genetically associated with the Xiaoliugou Caledonian granodiorite stock.
Mao Jingwen, Zhang Zhaochong, Zhang Zuoheng, Du Andao   +3 more
openaire   +3 more sources

Combining Paleomagnetic and Re‐Os Isotope Data to Date Hydrocarbon Generation and Accumulation Processes

Journal of Geophysical Research: Solid Earth, 2023
AbstractUnraveling the complex relationship between orogenesis and hydrocarbon formation and accumulation is challenging and is often hampered by physical and chemical overprints of younger events. The Permian reservoir in the Longmen Shan orogen, South China, is such an example, and its evolution has been hotly debated.
Jing Hu, Yong Zhang, Dong Jia, Adrian Muxworthy, David Selby, Yongxiang Li, Matthew J. Brzozowski, Guoqi Wei, Jian Cao, Hongwei Yin, Wei Li   +10 more
openaire   +1 more source

Dating crust-mantle separation: Re-Os isotopic study of mafic xenoliths from central Arizona

Geology, 1997
Mafic deep crustal and shallow upper mantle xenoliths hosted in the Chino Valley and Camp Creek latites of central Arizona have 187Os/188Os (0.216 to 1.51) ratios dramatically higher than values typical of mantle peridotite (
Sonia Esperança, Richard W. Carlson, Steven B. Shirey, Douglas Smith   +3 more
openaire   +1 more source

Simplified method for the Re–Os dating of molybdenite using acid digestion and isotope dilution ICP-MS

Analytica Chimica Acta, 2002
Abstract An analytical method was developed for Os–Re dating of molybdenite. The method is based on determination of Os and Re concentrations in molybdenite by isotope dilution inductively-coupled plasma mass spectrometry (ID-ICP-MS). Sample digestion and sample/spike equilibration were achieved by a two-stage autoclave-based procedure using a ...
Dmitry Malinovsky, Ilia Rodushkin, Douglas Baxter, Björn Öhlander   +3 more
openaire   +1 more source

Dating post-Archean lithospheric mantle: Insights from Re-Os and Lu-Hf isotopic systematics of the Cameroon Volcanic Line peridotites

Geochimica et Cosmochimica Acta, 2020
Abstract Highly depleted Archean peridotites have proven very amenable to Re-Os model age dating. In contrast, due to the increasing heterogeneity of mantle Os isotope compositions with time, the Re-Os system has not been as effective in dating post-Archean peridotites.
Liu, Jingao, Pearson, D. Graham, Shu, Qiao, Sigurdsson, Haraldur, Thomassot, Emilie, Alard, Olivier   +5 more
openaire   +3 more sources