Results 51 to 60 of about 689 (166)
Ta'dibThe purpose of this study is to determine the effect of the REACT learning strategy on problem-solving among fifth-grade students at Pekanbaru Public Elementary School.
Muhammad Fendrik +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
JP3M (Jurnal Penelitian Pendidikan dan Pengajaran Matematika), 2016 This research is aimed at improving the ability of students’ mathematical understanding through REACT strategy. This research method is a quasi-experimental study with the non randomized study design pretest-posttest control group design.
Linda Herawati
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
CHIMIA, 1986 1,1-Bis(3-indolyl)ethenes (3) react as 4π electron systems with dienophiles (e.g. acrylic acid methyl ester, tetracyanoethylene, benzyne, maleic anhydride, and 4-phenyl-1,2,4-triazoline-3,5-dione) to give cycloadducts of Diels-Alder type.
Ludwig Pfeuffer, Ulf Pindur
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Effect of context based REACT strategy on students’ conceptual understanding of heredity
Cogent EducationThe teaching of conceptual understanding is a key objective in the field of science education. But students, on average, do not adequately understand the concepts in a large number of science subjects.
Wuleta Ketema Abebe +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source