A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao +9 more
wiley +1 more source
Multiscale Perspectives on Char Oxidation: Reaction Regimes, Transport Phenomena, and Modeling Challenges. [PDF]
Yang J, Wu X, Yang L, Xu J, Wu S, Lai M.
europepmc +1 more source
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Self-organisation of complex dynamical systems: from synergetics to neuromorphic systems. [PDF]
Mainzer K.
europepmc +1 more source
Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad +7 more
wiley +1 more source
A Reaction-Diffusion Model for Capturing Mass Loss and Microstructure Evolution in Enzymatic Degradation of Poly(<i>ε</i>-Caprolactone) Films. [PDF]
Nansak N +4 more
europepmc +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Computational analysis of bioconvective and melting heat transfer in thixotropic nanofluid flow over a porous stretching surface. [PDF]
Shaheen M +7 more
europepmc +1 more source
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino +12 more
wiley +1 more source
Light-Driven Self-Pulsating Hydrogel with a Sliding-Delay Mechanism for Micro-Actuation and Microfluidic Applications. [PDF]
Zhou X, Peng H, Qiu Y, Li C.
europepmc +1 more source

