Results 71 to 80 of about 4,210,778 (298)

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Homogenization of a system of semilinear diffusion-reaction equations in an H^{1,p} setting

open access: yesElectronic Journal of Differential Equations, 2013
In this article, homogenization of a system of semilinear multi-species diffusion-reaction equations is shown. The presence of highly nonlinear reaction rate terms on the right-hand side of the equations make the model difficult to analyze. We obtain
Hari Shankar Mahato, Michael Bohm
doaj  

Large time monotonicity of solutions of reaction-diffusion equations in $R^N$ [PDF]

open access: yes, 2018
International audienceIn this paper, we consider nonnegative solutions of spatially heterogeneous Fisher-KPP type reaction-diffusion equations in the whole space.
Emmanuel Grenier   +3 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Existence of travelling waves for a reaction-diffusion system with a line of fast diffusion [PDF]

open access: yes, 2014
Accepted for publication in Appl. Math. Res. ExpressInternational audienceWe prove existence and uniqueness of travelling waves for a reaction-diffusion system coupling a classical reaction-diffusion equation in a strip with a diffusion equation on a ...
Laurent Dietrich, Dietrich, Laurent
core   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa   +3 more
wiley   +1 more source

Normal Forms of Hopf Bifurcation for a Reaction-Diffusion System Subject to Neumann Boundary Condition

open access: yesJournal of Applied Mathematics, 2015
A reaction-diffusion system coupled by two equations subject to homogeneous Neumann boundary condition on one-dimensional spatial domain (0,lπ) with l>0 is considered.
Cun-Hua Zhang, Xiang-Ping Yan
doaj   +1 more source

A Model of Porous Catalyst Accounting for Incipiently Non-isothermal Effects* [PDF]

open access: yes, 1999
An approximate model accounting for incipiently non-isothermal effects is derived from a well-known model of porous catalyst for appropriate, realistic limiting values of the parameters.
Vega de Prada, José Manuel   +3 more
core   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

open access: yesArthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee   +4 more
wiley   +1 more source

Reaction-diffusion systems with 1-homogeneous non-linearity

open access: yesElectronic Journal of Differential Equations, 2002
We describe the dynamics of a system of two reaction-diffusion equations with 1-homogeneous non-linearity. We show that either an order-preserving property holds and can be used in order to determine the limiting behaviour in some (invariant) sets or the
Matthias Bueger
doaj  

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