Results 161 to 170 of about 4,841,861 (299)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A scope of prebiotic neat reaction conditions and the mechanism of urea-assisted phosphorylations of alcohols. [PDF]

Nat Commun
Shvetsova A, Merzoud L, Lopez A, Fromentin E, Baudouin A, Chermette H, Daniel I, Fiore M, Strazewski P.   +8 more
europepmc   +1 more source

Coupling effect of reaction conditions on the catalytic activity of Cu-Mn composite oxide catalysts for toluene. [PDF]

RSC Adv, 2023
Wang Y, Liang X, Dai Y, Zou L, Sun D, Li F.   +5 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Galactooligosaccharide Production Using Immobilized <i>Aspergillus oryzae</i> β-Galactosidase, Part I: Characterization and Influence of Reaction Conditions. [PDF]

Int J Mol Sci
Antošová M, Adamíková JK, Polakovič M.   +2 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Synthesis of poly-functionalized pyrazoles under Vilsmeier-Haack reaction conditions

ARKIVOC, 2019
Aleksandr V. Popov, Valentina A. Kobelevskaya, Ludmila I. Larina, Igor B. Rozentsveig   +3 more
doaj   +1 more source

Application of the digital annealer unit in optimizing chemical reaction conditions for enhanced production yields. [PDF]

J Cheminform
Li SC, Wang PH, Su JW, Chiang WY, Yeh TL, Zhavoronkov A, Huang SH, Lin YC, Ou CH, Chen CY.   +9 more
europepmc   +1 more source

Bayesian Optimization-Assisted Screening to Identify Improved Reaction Conditions for Spiro-Dithiolane Synthesis. [PDF]

Molecules, 2023
Kondo M, Wathsala HDP, Ishikawa K, Yamashita D, Miyazaki T, Ohno Y, Sasai H, Washio T, Takizawa S.   +8 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source