Results 231 to 240 of about 14,968,723 (400)

Pathology of drug hypersensitivity reactions and mechanisms of immune tolerance

, 2022
Paul Thomson, Sean Hammond, Dean J. Naisbitt   +2 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Aqueous-Phase Multicomponent Reaction Mechanism for the Synthesis of Pyrido[2,3‑<i>d</i>]pyrimidines: A Theoretical Perspective. [PDF]

ACS Omega
Rufino VC, Amarante GW, Dos Santos HF.
europepmc   +1 more source

Steady-State Kinetics of the Autocatalytic Zymogen Activation: A Comparison with the Michaelis-Menten Reaction Mechanism

, 2019
Malgorzata Tyczynska, Justin Eilertsen, Santiago Schnell   +2 more
openalex   +1 more source

Reaction Mechanism and Kinetics for Ammonia Synthesis on the Fe(111) Surface.

Journal of the American Chemical Society, 2018
Jinxin Qian, Q. An, A. Fortunelli, Robert J. Nielsen, W. Goddard   +4 more
semanticscholar   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Boron-nitrogen fullerenes as electrocatalysts for nitrogen reduction: A computational study of affinity and reaction mechanism. [PDF]

iScience
Gazzari-Jara S, Cortés-Arriagada D, Chigo-Anota E, Miranda-Rojas S.   +3 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Revisiting Reaction Mechanism of Regioselective Disulfide-Catalyzed Photocatalytic Aerobic Oxidative Cleavage of 1-Arylbutadienes: A Computational Study. [PDF]

Chemphyschem
Fıstıkçı M, Lafzi F, Eşsiz S.
europepmc   +1 more source

Reaction Mechanisms [PDF]

Nature Physical Science, 1971
openaire   +1 more source