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Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Covalent functionalization by using blue light activated radicals: on the reaction mechanisms of arylazo sulfone binding on graphene. [PDF]

Nanoscale Adv
Mameli A, Kovtun A, Jones D, Benekou V, Palermo V, Bandini M, Melucci M.   +6 more
europepmc   +1 more source

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Inorganic reaction mechanisms

Dalton Transactions, 2020
Sam de Visser, Jonathan Rourke and Kylie Vincent introduce this Dalton Transactions themed collection on inorganic reaction mechanisms.
Sam P. de Visser, Jonathan P. Rourke, Kylie A. Vincent   +2 more
openaire   +2 more sources

Mechanisms of macromolecular reactions

History and Philosophy of the Life Sciences, 2022
During the past two decades, philosophers of biology have increasingly turned their attention to mechanisms of biological phenomena. Through analyses of mechanistic proposals advanced by biologists, the goal of these philosophers is to understand what a mechanism is and how mechanisms explain.
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Reaction mechanisms: pericyclic reactions

Annual Reports Section "B" (Organic Chemistry), 2012
This review summarizes a number of articles published in 2011 describing mechanisms of pericyclic reactions. The types of reactions studied were of the cycloaddition sort (e.g., [2+1], [2+2], [3+2], [4+2], etc.), as well as sigmatropic (e.g., [1,2], [1,3], [3,3] shifts, etc.), group transfer (e.g., ene), and electrocyclic types.
Edyta M. Greer, Christopher V. Cosgriff
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Reaction mechanisms: pericyclic reactions

Annual Reports Section "B" (Organic Chemistry), 2011
This report surveys the 2010 literature on mechanisms of pericyclic reactions. Among the newer concepts highlighted in this year's studies are the distortion-interaction model of reactivity, the importance of CH-π interactions in controlling selectivity, and the catalysis of pericyclic reactions by transition metals and organocatalysts.
Dean J. Tantillo, Jeehiun K. Lee
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Reaction mechanisms: polar reactions

Annual Reports Section "B" (Organic Chemistry), 2012
Highlights of mechanistic work pertaining to polar reactions published in 2012 are provided in this report. Such reactions cover a wide range of biologically, chemically and industrially-relevant processes, and although they have been broadly classified here, a number could span one or more general categories.
Hon Man Yau, Anna K. Croft
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Reaction mechanisms

2022
This chapter reviews the study of reaction rates that leads to an understanding of the mechanisms of reactions and the analysis into a sequence of elementary steps. It demonstrates how to construct rate laws from a proposed mechanism. It also outlines the elementary steps for simple rate laws that can be combined into an overall rate law: invoking the ...
Peter Atkins, Julio de Paula, James Keeler   +2 more
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Reaction Mechanisms

2016
AFTER I HAD BEEN in graduate school for several months, I decided to work in a group that studied photochemical reactions, those that are initiated by ultraviolet or visible light. My research advisor was interested in discovering new reactions and deducing experimentally how they occurred—the reaction mechanism. I remember my first group meeting where
Peter Atkins, Julio de Paula, David Smith   +2 more
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Reaction Mechanisms. Pericyclic Reactions

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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