Results 61 to 70 of about 2,991,068 (282)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Recycling and Degradation of Polyamides

Molecules
As one of the five major engineering plastics, polyamide brings many benefits to humans in the fields of transportation, clothing, entertainment, health, and more.
Lin Zheng, Mengjin Wang, Yaoqin Li, Yan Xiong, Chonggang Wu   +4 more
doaj   +1 more source

Reaction mechanisms in the 6Li+ 52Cr system

EPJ Web of Conferences, 2015
Reactions induced by the weakly bound 6Li projectile interacting with the intermediate mass target 52Cr are investigated. The choice of this particular reaction in our study is because it is proposed as a surrogate reaction [6Li(52Cr, d)56Fe*] for the ...
Pandey Bhawna, Prajapati P.M., Patel D., Desai V.V., Kumar H., Suranarayana S.V., Nayak B.K., Saxena Alok, Jakhar S., Rao CVS, Basu T.K.   +10 more
doaj   +1 more source

Mechanisms of flavoprotein‐catalyzed reactions [PDF]

European Journal of Biochemistry, 1989
Flavoproteins are a class of enzymes catalyzing a very broad spectrum of redox processes by different chemical mechanisms. This review describes the best studied of these mechanisms and discusses factors possibly governing reactivity and specificity.
Ghisla, Sandro, Massey, Vincent
openaire   +5 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A Trajectory-Based Method to Explore Reaction Mechanisms

Molecules, 2018
The tsscds method, recently developed in our group, discovers chemical reaction mechanisms with minimal human intervention. It employs accelerated molecular dynamics, spectral graph theory, statistical rate theory and stochastic simulations to uncover ...
Saulo A. Vázquez, Xose L. Otero, Emilio Martinez-Nunez   +2 more
doaj   +1 more source

High-energy exclusive leptoproduction of vector mesons

, 1996
The physics of diffractive vector meson production in virtual photon nucleon scattering at NMC energies is reviewed. A particular attention is paid to the physical aspects of the reaction and how they influence the observables.
Bauer, Brodsky, Brodsky, Di Giacomo, Donnachie, Donnachie, Dosch, Dosch, Dosch, Dosch, EMC, Low, Nachtmann, Nachtmann, Nemchick, NMC, Nussinov, Radyushkin, Ryskin, Thierry Gousset   +19 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Isotopic Scaling in Nuclear Reactions

, 2000
A three parameter scaling relationship between isotopic distributions for elements with Z$\leq 8$ has been observed that allows a simple description of the dependence of such distributions on the overall isospin of the system.
A. Majumder, A. S. Botvina, Aage Bohr, B. A. Li, Bao-An Li, C. K. Gelbke, C. K. Gelbke, G. J. Kunde, G. Verde, H. S. Xu, H. S. Xu, I. Bombaci, J. Brzychczyk, J. Randrup, J. Tõke, M. B. Tsang, M. D’Agostino, R. Laforest, R. Wada, S. Albergo, S. R. Souza, Scott Pratt, V. E. Viola, V. V. Volkov, V. Weisskopf, W. A. Friedman, W. A. Friedman, W. A. Friedman, W. Friedman, W. G. Lynch, W. U. Schroeder   +30 more
core   +1 more source