Results 61 to 70 of about 3,008,459 (388)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes [PDF]

, 2010
The electrochemical reduction of carbamazepine in acetonitrile (ACN) and dimethylformamide (DMF) using a glassy carbon electrode and microelectrodes has been studied.
Anicet, Bardy, Cannes, Cantú, Carvalho, Farrington, Fisher, García-García, Hall, Jones, Jönsson, Kim, Longinotti, Mashayekhi, Moses, Nicholson, Pilgrim, Savéant, Sevilla, Spiller, Subramanian, Sullivan, Weaver   +22 more
core   +1 more source

Macrokinetics of the deterioration of cement-based grouting material for predicting its service life under acid rain attack

Heritage Science, 2023
Cement-based grouting material is widely used to reinforce the unsafe rock and control seepage of rock-carved relics although it is considered inappropriate in protection of ancient sites.
Wenjing Hu, Shiqiang Fang, Lina Xie, Xueqiang Chen, Bingjian Zhang   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Flame Enhancement and Quenching in Fluid Flows [PDF]

, 2002
We perform direct numerical simulations (DNS) of an advected scalar field which diffuses and reacts according to a nonlinear reaction law. The objective is to study how the bulk burning rate of the reaction is affected by an imposed flow.
Abel M, Abel M, Alexander Kiselev, Audoly B, Avellaneda M, Berestycki H, Bradley D, Chandrasekhar S, Drazin P G, Fife P C, Kanel Ya, Kolmogorov A N, Leonid Ryzhik, Natalia Vladimirova, Oleg Ruchayskiy, Pelcé P, Peter Constantin, Ronney P D, Taylor G I, Vladimirova N, Volpert A, Williams F A, Zeldovich Ya B   +22 more
core   +2 more sources

Evaluation of Front Morphological Development of Reactive Solute Transport Using Behavior Diagrams

Terrestrial, Atmospheric and Oceanic Sciences, 2009
While flowing through porous medium, ground water flow dissolves minerals thereby in creasing medium porosity and ultimately permeability. Reactive fluid flows preferentially into highly permeable zones, which are therefore dissolved most rapidly ...
Jui-Sheng Chen, Yuan-Yao Chang, Chen-Wuing Liu   +2 more
doaj   +1 more source

Kinetic and Mechanistic Studies for the Gas-phase Reaction of Ozone with 2, 3-Dimethyl-2-Butene and 1, 3-Butadiene

مجلة بغداد للعلوم, 2017
The reactions of ozone with 2,3-Dimethyl-2-Butene (CH3)2C=C(CH3)2 and 1,3-Butadiene CH2=CHCH=CH2 have been investigated under atmospheric conditions at 298±3K in air using both relative and absolute rate techniques, and the measured rate coefficients are
Baghdad Science Journal
doaj   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The intrinsic rate constants in diffusion-influenced reactions

Faraday Discussions, 2016
Intrinsic rate constants play a dominant role in the theory of diffusion-influenced reactions, but usually as abstract quantities that are implicitly assumed to be known. However, recently it has become clear that modeling complex processes requires explicit knowledge of these intrinsic rates.
Adithya, Vijaykumar, Peter G, Bolhuis, Pieter Rein, Ten Wolde   +2 more
openaire   +3 more sources