Sequential anti-cytomegalovirus response monitoring may allow prediction of cytomegalovirus reactivation after allogeneic stem cell transplantation [PDF]
, 2012 Background: Reconstitution of cytomegalovirus-specific CD3+CD8+ T cells (CMV-CTLs) after allogeneic hematopoietic stem cell transplantation (HSCT) is necessary to bring cytomegalovirus (CMV) reactivation under control. However, the parameters determining
Bader, Peter +17 more
core +7 more sources
Mediterranean Journal of Hematology and Infectious Diseases, 2019 CMV associated tissue-invasive disease is associated with a considerable risk of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Recently, the terminase inhibitor letermovir (LMV) has been approved for prophylaxis
Jochen J Frietsch +8 more
doaj +1 more source
Fault reactivation by fluid injection: Controls from stress state and injection rate [PDF]
, 2018 We studied the influence of stress state and fluid injection rate on the reactivation of faults. We conducted experiments on a saw-cut Westerly granite sample under triaxial stress conditions.
Brantut, Nicolas +2 more
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When awareness gets in the way : reactivation aversion effects resolve the generality/specificity paradox in sensorimotor interference tasks [PDF]
, 2020 Interference tasks combining different distractor types usually find that between-trial adaptations (congruency sequence effects [CSEs]) do not interact with each other, suggesting that sensorimotor control is domain-specific. However, within each trial,
Maylor, Elizabeth A. +1 more
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Reactivation of hepatitis B virus with immune-escape mutations after ocrelizumab treatment for multiple sclerosis [PDF]
, 2019 Ocrelizumab is an anti-CD20 monoclonal antibody for the treatment of multiple sclerosis (MS) that is closely related to rituximab. We describe a case of hepatitis B virus (HBV) reactivation in an MS patient with resolved HBV infection receiving ...
Altieri, Marta +11 more
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Novel Group of AChE Reactivators—Synthesis, In Vitro Reactivation and Molecular Docking Study
Molecules, 2018 The acetylcholinesterase (AChE) reactivators (e.g., obidoxime, asoxime) became an essential part of organophosphorus (OP) poisoning treatment, together with atropine and diazepam.
David Malinak +4 more
doaj +1 more source
Clinical Case: SARS-CoV-2 Reactivation After a Heavy Workout
Acta Medica Bulgarica, 2020 We present a clinical case of a patient with reactivation of SARS-CoV-2 infection after strenuous exercise in the gym. Reactivation of the virus was confirmed after detecting SARS-CoV-2 in a nasopharyngeal swab sample using real-time polymerase chain ...
Marchev S. +2 more
doaj +1 more source
Impact of IFN lambda 3/4 single nucleotide polymorphisms on the cytomegalovirus reactivation in autologous stem cell transplant patients [PDF]
, 2018 Cytomegalovirus (CMV) infection represents one of the main cause mortality after Stem Cell Transplantation. Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic ...
Angeletti, S +13 more
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Metallochaperones Are Needed for Mycobacterium tuberculosis and Escherichia coli Nicotinamidase-Pyrazinamidase Activity. [PDF]
, 2020 Mycobacterium tuberculosis nicotinamidase-pyrazinamidase (PZAse) is a metalloenzyme that catalyzes conversion of nicotinamide-pyrazinamide to nicotinic acid-pyrazinoic acid. This study investigated whether a metallochaperone is required for optimal PZAse
Antiparra, R +10 more
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Human Cytomegalovirus Primary Infection and Reactivation: Insights From Virion-Carried Molecules
Frontiers in Microbiology, 2020 Human cytomegalovirus (HCMV), a ubiquitous beta-herpesvirus, is able to establish lifelong latency after initial infection. Periodical reactivation occurs after immunosuppression, remaining a major cause of death in immunocompromised patients.
Yu-Qing Wang +2 more
doaj +1 more source