Results 71 to 80 of about 325,287 (328)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Design of molecularly imprinted polymers for sensors and solid phase extraction [PDF]

open access: yes, 2002
This thesis presents broadly the applications of molecularly imprinted polymers in sensors and solid phase extraction. Sensors for creatine and creatinine have been reported using a novel method of rational design of molecularly imprinted polymers ...
Subrahmanyam, Sreenath
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Development of a reactive extraction process for isobutyl isobutyrate formation intensified by bifunctional ionic liquid

open access: yesChemical Engineering Science: X, 2019
Isobutyl isobutyrate (IBIBE) is a typical long-chain ester widely used as a solvent, additive, or raw material. To address problems such as acidic waste emission and tedious downstream separation in traditional synthesis routes, a reactive extraction ...
Qian Zeng   +4 more
semanticscholar   +1 more source

The effect of fermentation broth composition on removal of carboxylic acids by reactive extraction with Cyanex 923

open access: yes, 2020
This paper presents results of liquid-liquid extraction of carboxylic acids, particularly succinic acid (Suc), from one-, two-and multi-component model solutions, and from a fermentation broth with 0.1 and 0.4 mol/L Cyanex 923 (solvating extractant ...
Agnieszka Krzyżkowska, M. Regel-Rosocka
semanticscholar   +1 more source

Reactive Extraction of Acetic Acid from Aqueous Sodium Acetate Waste [PDF]

open access: yesNature Environment and Pollution Technology
The recovery of acetic acid from aqueous sodium acetate using traditional methods is costly and energy-intensive. The current study focuses on exploring a synergetic reactive extraction methodology to extract acetic acid from aqueous sodium acetate waste.
Ganesh Bhoj, Sunita Patil, Sharada Gadale and Shambala Gadekar-Shinde
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Minimum Solvent Flow Rate for Counter-Current Liquid-Liquid Extraction Columns

open access: yesChemical Engineering Transactions, 2014
A simple scheme to determine the minimum solvent flow rate for counter-current extraction columns is obtained and its validity is verified using two case studies. An infinite number of equilibrium stages are simplified to a single equilibrium stage.
J. Bonet   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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