Results 51 to 60 of about 5,518,673 (258)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Wave-to-Wire Power Maximization Control for All-Electric Wave Energy Converters with Non-Ideal Power Take-Off

Energies, 2019
The research presented in this paper investigates novel ways of optimizing all-electric wave energy converters for maximum wave-to-wire efficiency. In addition, a novel velocity-based controller is presented which was designed specifically for wave-to ...
Marios Charilaos Sousounis, Jonathan Shek   +1 more
doaj   +1 more source

Secondary control with reduced communication requirements for accurate reactive power sharing in AC microgrids

IET Smart Grid, 2023
A secondary control method is proposed for accurate reactive power sharing as well as frequency and voltage restoration in islanded AC microgrids (MGs).
Mehdi Baharizadeh, Mohammad Sadegh Golsorkhi, Mehdi Savaghebi   +2 more
doaj   +1 more source

FPGA-Based Realization of Self-Optimizing Drive-Controllers [PDF]

, 2009
Paiz C, Hagemeyer J, Pohl C, et al. FPGA-Based Realization of Self-Optimizing Drive-Controllers. In: IEEE Industrial Electronics Society, Institute of Electrical and Electronics Engineers, Keisoku-jidō-seigyō-gakkai, Universidade do Porto, eds.
Keisoku-jidō-seigyō-gakkai, Universidade do Porto, J. Hagemeyer, U. Ruckert, J. Bocker, Peters, Wilhelm, Institute of Electrical and Electronics Engineers, M. Porrmann, Paiz, Carlos, C. Pohl, Schulz, Bernd, Porrmann, Mario ; https://orcid.org/, Pohl, Christopher, B. Schulz, Böcker, Joachim, W. Peters, Rückert, Ulrich, Hagemeyer, Jens, IEEE Industrial Electronics Society, C. Paiz   +19 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A comparative simulative study to determine controller schemes of static var compensator (svc) for stability of power system

Mehran University Research Journal of Engineering and Technology
A key challenge in ensuring and maintaining power system stability is the rapid management of power transients. These voltage fluctuations arise from various causes, such as sudden load changes or network faults, which, if not addressed quickly, can lead
Osama Butt, Muhammad Mohsin, Rasmia Irfan, Husnain Ashfaq, Kashif Habib   +4 more
doaj   +1 more source

VOLTAGE PROFILE IMPROVEMENT WITH APPLICATION OF DIFFERENTLY OPTIMIZED FACTS CONTROLLERS [PDF]

Carpathian Journal of Electrical Engineering
This research work presents a novel individual and Hybrid MGA and IGWO was utilized to develop FACTS-controlled optimization model for improvement of bus voltage profiles.
Joel R. SUTTER, John N. NDERU, Ariel M. MUTEGI   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Point of Common Coupling Voltage Modulated Direct Power Control of Grid-Tied Photovoltaic Inverter for AC Microgrid Application

International Transactions on Electrical Energy Systems, 2023
A direct power control (DPC) approach is proposed in this study for a grid-tied photovoltaic (PV) voltage source inverter (VSI) to regulate active and reactive power flow directly in between utility grid and microgrid (MG) by controlling point of common ...
Shameem Ahmad, Hamza Mubarak, Umme Kulsum Jhuma, Tofael Ahmed, Saad Mekhilef, Hazlie Mokhlis   +5 more
doaj   +1 more source