Results 81 to 90 of about 3,938,090 (292)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Reactive compatibilization strategies for mixed polyolefin waste toward food packaging applications

open access: yesDiscover Polymers
Plastic waste from packaging materials has caused significant environmental harm. This has necessitated the development of industrially scalable upcycling techniques for mixed polyolefin waste streams.
Silas T. Timu, Tanyaradzwa S. Muzata
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Processing of intractable polymers using reactive solvents: 1. Poly(2,6-dimethyl-1,4-phenylene ether)/epoxy resin [PDF]

open access: yes, 1994
A new processing route for poly(2,6-dimethyl-1,4-phenylene ether) (PPE), an intractable polymer on account of its thermal and oxidative sensitivity, was explored.
Venderbosch, R.W.   +5 more
core   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Processing of (in)tractable polymers using reactive solvents, 4: Structure development in the model system poly(ethylene)/styrene

open access: yes, 1998
The use of reactive solvents provides a unique opportunity to extend the processing characteristics of both intractable and standard (tractable) polymers beyond existing limits.
Meijer, H.E.H.   +7 more
core   +1 more source

Reactive power compensation and start-up energy waste reduction of linter device electric motor [PDF]

open access: yesE3S Web of Conferences
In primary cotton processing enterprises, all electricity consumers, including the electricity consumption of the linter, especially the reactive power, are the compensation of the reactive power consumption. In particular, it is seen that the high power
Obidov Avazbek, Shamshitdinov Maqsudbek
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Processing in intractable polymers using reactive solvents: 3. Mechanical properties of poly(2,6-dimethyl-1,4-phenylene ether) processed by using various epoxy resin systems [PDF]

open access: yes, 1995
The rather intractable polymer poly(2,6-dimethyl-1,4-phenylene ether) (PPE) can easily be processed by using epoxy resin as a reactive solvent. In this reactive solution processing technique, PPE is dissolved in epoxy resin at elevated temperatures and ...
Venderbosch, R.W.   +5 more
core   +2 more sources

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