Results 161 to 170 of about 173,657 (302)

Trends and Challenges in Multistep Continuous Flow Synthesis. [PDF]

open access: yesJACS Au
Chen J   +9 more
europepmc   +1 more source

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

open access: yesChemistry – A European Journal, EarlyView.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere   +2 more
wiley   +1 more source

Expedient Discovery of a Metallaphotoredox Cyanomethylation for Synthesizing α‐Aryl Nitriles

open access: yesChemistry – A European Journal, EarlyView.
A metallaphotoredox cyanomethylation reaction has been developed for the synthesis of valuable α‐aryl nitrile intermediates. The methodology was successfully applied to diverse medicinally‐relevant substrates, providing an expedient route to anti‐cancer Senexin compounds, while also removing the need for toxic cyanide reagents. The mechanism was probed
Gemma C. Cook   +6 more
wiley   +1 more source

Safety assessment of the process EREMA Vacurema Advanced used to recycle post-consumer PET into food contact materials. [PDF]

open access: yesEFSA J
EFSA Panel on Food Contact Materials (FCM)   +16 more
europepmc   +1 more source

Fusion Reactor Safety

open access: yesEurophysics News, 1998
openaire   +1 more source

Harnessing Acoustic Cavitation Energy for the Selective Degradation of Impurities in Glucose Syrup

open access: yesChemistry – A European Journal, EarlyView.
The energy released during the implosion of acoustic cavitation bubbles can be harnessed and selectively transferred to a target solute, enabling its specific decomposition without degrading other solutes present in the solution. This proof of concept was demonstrated in the degradation of impurities present in trace amount in glucose syrup.
Shambel Getachew Wasse   +2 more
wiley   +1 more source

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