Results 211 to 220 of about 304,455 (291)

Improving the Understandability of Clinical Guidelines: Development and Evaluation of a GPT-4-Based Pipeline.

J Med Internet Res
Jones MD, Torgbi M, Tayyar Madabushi H.
europepmc   +1 more source

Utility of ChatGPT-4o in Creating Patient Handouts in Ophthalmology: A Comparison With American Academy of Ophthalmology Educational Materials. [PDF]

Transl Vis Sci Technol
Wu LL, Hong AT, Davuluru SS, Moreno-Diaz EA, Gutiérrez-Hernández JC, Martinez-Camarillo JC, Xu BY, Zhang-Nunes S.   +7 more
europepmc   +1 more source

Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman, Carli M. Tops, Jelmer Legebeke, Ting Yang, Marcos Díaz Gay, Diantha Terlouw, Lisa E. E. L. O. Lashley, Stefan Aretz, Anna K. Sommer, Mariona Terradas, Laura Valle, Richarda M. de Voer, Ludmil B. Alexandrov, Hans Morreau, Tom van Wezel, Maartje Nielsen   +15 more
wiley   +1 more source

Bottom‐Up Coacervate‐Based Artificial Cells: Integrating Cellular Hallmarks into Complex Life‐Like Systems

Angewandte Chemie, EarlyView.
Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo, Angshuman Das, Madelief A. M. Verwiel, Jan C. M. van Hest   +3 more
wiley   +2 more sources

Leveraging Large Language Models to Improve the Readability of German Online Medical Texts: Evaluation Study. [PDF]

JMIR AI
Miftaroski A, Zowalla R, Wiesner M, Pobiruchin M.   +3 more
europepmc   +1 more source

Genetic Risk and High Burden of Depression and Suicide in the Maya‐Mestizo Population of Yucatán, México

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Major depression and suicide are critical public health concerns, particularly in underrepresented populations with unique genetic and sociocultural contexts. The Maya‐mestizo population presents the highest suicide rates in the country but remains understudied in psychiatric genetics. This study evaluated the association between three genetic
Marta Menjivar, Erandi Bravo, Margarita Rivera‐Balancan, Barbara Itzel Pena Espinoza   +3 more
wiley   +1 more source

Decoding Carbon Dot Purity by Nuclear Magnetic Resonance

Angewandte Chemie, EarlyView.
NMR spectroscopy tracks the removal of molecular and oligomeric impurities in carbon dots, enabling a (semi)quantitative evaluation of their purity through integrated peak analysis. ABSTRACT Carbon dots (CDs) have attracted increasing attention in recent years and have been widely explored in many fields.
Yalei Hu, Alberto Bianco
wiley   +2 more sources

Assessing ChatGPT vs. evidence-based online responses for polycystic ovary syndrome self-management and education: an international cross-sectional blinded survey of healthcare professionals. [PDF]

Front Digit Health
Graca S, Dallaway A, Alloh F, Randeva HS, Kite C, Kyrou I.   +5 more
europepmc   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Online Patient Education Materials for Pediatric Septic Arthritis Exceed Recommended Reading Levels: A Readability Analysis. [PDF]

Cureus
Pettinelli NJ, Blackwell MC, Schwartz M.
europepmc   +1 more source