Results 81 to 90 of about 1,227,206 (306)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

BIAS GENDER DALAM BUKU TEKS PELAJARAN BAHASA INDONESIA SEKOLAH MENENGAH ATAS

open access: yesRetorika, 2019
: Gender Bias in Indonesian Language Textbook in Senior High School.This research to described gender bias based on the subject-object viewpoint and author-reader viewpoint of Sara Mills theory on textbook.
Dewi Ulfah, Idawati Garim, Sultan Sultan
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Multi-disciplinary perspectives in teaching FL reading skills [PDF]

open access: yes, 2018
The aim of the paper is to discuss theoretical perspectives which have exerted most impact on empirical research and education concerning foreign language literacy. Two theoretical orientations are the foci of the article: a psycholinguistic perspective,
Junior College multi-disciplinary conference : research, practice and collaboration : Breaking Barriers : annual conference 2018   +1 more
core  

The Trojan ass : Asinarius as mock epic [PDF]

open access: yes, 2013
The medieval narrative poem Asinarius (late 12th early 13th c.) has commonly been considered a fairy tale ante litteram, predating the self-conscious development of the literary genre from early modem times onward.
Praet, Stijn
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

El lector como usuario: implicaciones didácticas

open access: yesInvestigaciones Sobre Lectura, 2016
This article analyzes the figure of the reader and the challenges facing this through the transformations that occur in the digital world from the perspective of the teaching-learning.
Concepción López-Andrada
doaj   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Using cost effectiveness analysis; a beginners guide [PDF]

open access: yes, 2006
Objective ‐ This report seeks to describe the key elements of cost effectiveness analysis (CEA) and to demonstrate how such analysis may be used in the library environment. Methods ‐ The paper uses a step‐by‐step approach to walk the non‐economist
Hulme, C.
core   +1 more source

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