Results 81 to 90 of about 99,565 (264)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
El lector como usuario: implicaciones didácticas
Investigaciones Sobre Lectura, 2016 This article analyzes the figure of the reader and the challenges facing this through the transformations that occur in the digital world from the perspective of the teaching-learning.
Concepción López-Andrada
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Witold Gombrowicz w kalejdoskopie recepcji
Postscriptum Polonistyczne, 2020 Seen through the perspective of reception, the works of Witold Gombrowicz constitute a wide range of receptive proposals, selectively updated in the constant dynamic of the interactive discourse between the literary subject and the reader.
Dimitrina Hamze
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
CLELEjournalIn this paper, the concept of Ordinary Magic is used to further demonstrate in how far challenging picturebooks can be used as springboards for critical conversations about mental and emotional well-being, perspective-taking, and emotion regulation in an
Barbara Katharina Reschenhofer
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Aproximações entre a história da leitura e da alfabetização [PDF]
Revista da Faculdade de Letras. Série de História, 2016 The discussions in recent decades having as object the history of reading highlighted the autonomy of the individual reader in the interpretation of written texts. In this context we emphasize that Paulo Freire and Roger Chartier give to the reader his
Fabiana Sena, Wojciech Andrzej Kulesza
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Reading, reception and constructions significant in texts of black writers
Cadernos de Letras da UFF, 2017 The following work reflects on the importance of the subject reader in the sphere of literary production, as from authors as Jauss (1979), Eagleton (2006), Orlandi (2006), among others.
Taise Campos dos Santos Pinheiro de Souza
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