Results 71 to 80 of about 540,883 (211)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Construction of the Enemy City in the Hebrew Bible: A Case of Thirdspacing [PDF]

open access: yesUniversity of Bucharest Review. Literary and Cultural Studies Series, 2016
Scholarship defines Thirdspace as the production of space through usage (Lefebvre) and as a spatial concept in which traditional binary oppositions dissolve (Soja).
Karolien Vermeulen
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Personalizing the Reading Experience: Implementing the Reader-Response Approach in TEFL Contexts [PDF]

open access: yesمجلة العلوم التربوية بکلية التربية، جامعة الغردقة
This article presents an overview of the Reader-Response Approach and its significance in personalizing the reading experience in contexts of teaching English as a Foreign Language (TEFL).
ا.د. عيد عبدالواحد علي درويش   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Learning About Ourselves and Others: Developing Intercultural Understandings through Global Literature

open access: yesWOW Stories, 2013
One of the most powerful ways to grow professionally as an educator is to participate in a study group or learning community. This type of professional development brings together a group of people who engage in sustained inquiry on a question related to
Prisca Martens , Ray Martens
doaj  

Reader Response: <i>D313Y</i> Variant in Fabry Disease: A Systematic Review and Meta-analysis. [PDF]

open access: yesNeurology, 2023
Lackova A   +4 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy