Results 101 to 110 of about 421,956 (305)

Industrialisation and Human Social Development: Charles Dickens’ Hard Times as a Conscience to Sciences [PDF]

open access: yes, 2018
This critical research work aims at investigating on Dickens\u27s outstanding academy which is incharge of all boys\u27 and girls\u27 education in the Britain\u27s 19th century.
YEKINI, I. (Ibrahim)
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Interpreting texts and the matter of context: Examples from the Book of Ruth

open access: yesVerbum et Ecclesia, 2019
This article aims to explore the matter of context in biblical exegesis and interpretation. Several exegetical approaches are discussed, namely, text-immanent, intertextual comparison, reader-response criticism, which is subdivided into feminist and ...
Gerda de Villiers
doaj   +1 more source

X: Poems & Anti-Poems by Shane Rhodes [PDF]

open access: yes, 2014
A review of Shane Rhodes\u27 X: Poems & Anti-Poems. This review focuses on the link between language and landscape, and considers the ways in which that link, reflected in Rhodes\u27 work, comments upon the use of language as an oppressive tool in the ...
Miller, Tom
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

\u3cem\u3eThe Chronicles of Narnia\u3c/em\u3e, and How C.S. Lewis Created Christian Fantasy Fiction [PDF]

open access: yes, 2015
C.S. Lewis was a pioneer in combining the ideas of fantasy and Christian literature, before the fantasy genre alone was even acknowledged. Christian fantasy fiction, as a fiction sub-genre, can be identified as a piece of fiction with fantastical ...
Callow, Amanda
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Sarah laughed: women\u27s voices in the Old Testament [PDF]

open access: yes, 1996
Reviewed Book: Dennis, Trevor. Sarah laughed: women\u27s voices in the Old Testament.
McLeese, Constance E.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Reader-response theory: Using literary works to promote EFL students’ critical reading skills

open access: yesStudies in English Language and Education
This study investigated the combination of literary works and reader-response theory as a form of literary criticism to promote EFL students’ critical reading skills.
Hamzah Puadi Ilyas   +2 more
doaj   +1 more source

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