Results 41 to 50 of about 422,269 (304)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The students’ reflective writing manifestation of reader-response literary analysis

Edulite: Journal of English Education, Literature, and Culture, 2019
This article presents reflective writing manifestation in Reader-response literary analysis. The article is aimed at finding out how the reflective writing is manifested in the students’ Reader-response of literary analysis.
R. Bunga Febriani
doaj   +1 more source

On tit for tat: Franceschini and Maisano versus ANVUR regarding the Italian research assessment exercise VQR 2011-2014

, 2017
The response by Benedetto, Checchi, Graziosi & Malgarini (2017) (hereafter "BCG&M"), past and current members of the Italian Agency for Evaluation of University and Research Systems (ANVUR), to Franceschini and Maisano's ("F&M") article (2017 ...
Abramo, Giovanni, D'Angelo, Ciriaco Andrea   +1 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The reception of antiquity in nineteenth-century British literature – an attempt at theoretical synthesis

Journal of Language and Cultural Education, 2018
The aim of the paper is to make an attempt of theoretical synthesis connected with the idea of reception studies. It presents major aspects which are crucial for understanding the reception studies, especially for the reception of antiquity in Victorian ...
Buda Agata
doaj   +1 more source

Транзакційна теорія Луїзи М. Розенблатт: між текстом і читачем [PDF]

, 2013
У статті розглянуто транзакційну теорію Луїзи Мішель Розенблатт як певну проміжну ланку між «новою критикою» й теорією читацького відгуку і водночас як самостійну літературознавчу теорію.
Анісімова, Людмила Вікторівна
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Inside Alex’s Mind: Language, Music, and Moral Engagement in A Clockwork Orange

Melius: Journal of Narrative and Language Studies
This article examines Anthony Burgess’s A Clockwork Orange through the lens of Reader-Response Theory (Reception Theory, Reader-Oriented Criticism), particularly the perspectives of Wolfgang Iser and Stanley Fish.
Necmettin Kaplan
doaj   +1 more source

“(Нео)антропоцентризм" у літературознавстві США ХХ століття [PDF]

, 2013
У статті з’ясовано причини появи у літературознавстві США ХХ століття теорій, об’єктом дослідження в яких постає читач/читацька спільнота, та досліджується проблема становлення теорії читацького відгуку як літературознавчого “(нео)антропоцентричного ...
Анісімова, Людмила Вікторівна
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source