Results 71 to 80 of about 421,956 (305)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Begabte Schwindlerinnen. Über die Inszenierungen der Lüge bei Ljudmila Ulickaja

open access: yesCahiers d’Études Germaniques, 2015
In her novel, Women’s Lies (Russian title: Skvoznaja linija [Through Line], 2002), Lyudmila Ulickaja creates a veritable typology of female lies and provides an explicit reflection on the specific characteristics of female tall tales.
Christiane SOLTE-GRESSER
doaj   +1 more source

Towards critical literacy : literature and teachers' reactions to reader-response theories : a thesis presented in fulfilment of the requirements for the degree of Master of Arts in Second Language Teaching at Massey University [PDF]

open access: yes, 1999
Much poststructuralist literary theory, in particular that derived from reader-response theories, points to the need for the development in readers of a more critical literacy.
Brown, R. A. Julie
core  

Ways of not reading Gertrude Stein [PDF]

open access: yes, 2015
I situate the controversial critical strategies of “distant reading” and “surface reading” in the reception history of Gertrude Stein, an author whose work was frequently declared “unreadable.” I argue that an early twentieth-century history of ...
Cecire, Natalia
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Theoretical Views Underlying the Selection of Classroom Activities: Paying Attention to the Classroom of English Literature in EFL Context

open access: yesTEFLIN Journal, 2003
This essay reviews literature on the theoretical views underlying the selection of activities for classrooms of English literature teaching in EFL context.
Yazid Basthomi
doaj   +3 more sources

Childhood Hermeneutics and the Uniqueness of the Aesthetic Reading of Children’s Literature

open access: yesEncyclopaideia
The purpose of this paper is to reflect on the uniqueness of the aesthetic reading of children’s literature and child hermeneutics as foundations for reading education.
Stefania Carioli
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

The Role of Implied Reader in the Realm of Literary Criticism [PDF]

open access: yesپژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2018
This article aims to examine the process of text reading and understanding, based on the concept of implied reader, for the definition of which, we have synthesized herein the seemingly antithetical methods of ‘authorial’ and ‘reader-oriented’ criticism.
Hossein Safi Pirlooje
doaj  

Psychoanalytic Literary Criticism: Using Holland’s DEFT Model as a Reader Response Tool in the Language Classroom

open access: yesLanguage and Psychoanalysis, 2013
Language students tend to struggle with literature because they find psychological and socio-cultural implications embedded in literary texts difficult to understand and discuss (Kramsch, 1996).
Lubie Grujicic-Alatriste
doaj   +1 more source

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