Results 71 to 80 of about 5,784,718 (274)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Taking Risks. A Reading of Oscar Wilde's The Picture of Dorian Gray

open access: yesMiscelánea: A Journal of English and American Studies, 1994
The aim of this paper is to analyse Oscar Wilde's The Picture of Dorian Gray  from a postmodernist standpoint. By drawing on a variety of critical  perspectives, such as psychoanalysis, deconstruction, and reader-response  criticism, it tries to suggest
Isabel Fraile Murlanch
doaj   +1 more source

Architectural Criticism between Public Debate and Autonomous Discipline (8)

open access: yes, 2016
Architecture Criticism vs. the Public : ‘Mirvish+Gehry Toronto’ A Case Study Kristen Gagnon Azrieli School of Architecture & Urbanism, Carleton University Stemming from my doctoral research on the current conditions in Canadian popular architecture ...
Mapping Architectural Criticism
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

'Response and Responsibility: Theories of the Implied Reader in Children's Literature Criticism'

open access: yes, 2004
Reader Response Theory remains popular within Children's Literature Criticism. It seems to offer a sensible resolution to the question of whether meaning derives from text or reader.
Cocks, Neil
core   +5 more sources

НОРМАН Н. ГОЛЛАНД. ЄДНІСТЬ ІДЕНТИЧНІСТЬ ТЕКСТ Я-САМ

open access: yesСинопсис: текст, контекст, медіа, 2014
Переклад із англійської та коментарі Людмили Анісімової   Перекладено за виданням: Norman N. Holland. UNITY IDENTITY TEXT SELF // Reader-response criticism: From Formalism to Post-Structuralism / Ed. Jane P. Tompkins.
Liudmyla Anisimova
doaj  

Kryminalny teatr teorii Normana Hollanda

open access: yesAnnales Universitatis Paedagogicae Cracoviensis. Studia Poetica, 2019
Artykuł skupia się na Death in a Delphi Seminar: A Postmodern Mystery (1995) Normana N. Hollanda oraz na relacjach między tą powieścią i Hollandowską wersją reader-response theory.
Anna Skubaczewska-Pniewska
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Can Machines Read (Literature)?

open access: yesUmanistica Digitale, 2019
In this essay, we reflect on distant reading as one of the various takes on reading that currently prevail in literary scholarship as well as the teaching of literature.
Mike Kestemont, Luc Herman
doaj   +1 more source

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