Results 61 to 70 of about 3,141,083 (255)

Dynamic profiles and transcriptional preferences of histone modifications during spermiogenesis.

open access: yesEndocrinology, 2020
During spermiogenesis, extensive histone modifications take place in developing haploid spermatids besides morphological alterations of the genetic material to form compact nuclei.
Yin-Chuan Li   +9 more
semanticscholar   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

A Degenerate Peptide Library Approach to Reveal Sequence Determinants of Methyllysine-Driven Protein Interactions

open access: yesFrontiers in Cell and Developmental Biology, 2020
Lysine methylation facilitates protein-protein interactions through the activity of methyllysine (Kme) “reader” proteins. Functions of Kme readers have historically been studied in the context of histone interactions, where readers aid in chromatin ...
Ariana Kupai   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

DELVING THE HOOK SENTENCE IN ARGUMENTATIVE ESSAY: FINDING THE WRITERS’ PREFERENCES OF CATCHY SENTENCE

open access: yesJurnal Educatio FKIP UNMA, 2020
Hook sentences as an opener and attention grabber in introductory paragraph play important role to make readers keep reading an essay. This means the structure and preferences to produce the hook is a key point to an interesting essay.
Yenni Arif Rahman
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Recognition of boys as readers through a social justice lens

open access: yes, 2020
This paper considers whether societal changes are making space for some working-class boys to go against the grain and foster positive reader identities.
Laura Scholes
semanticscholar   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The Readers’ Milieu 1917-1920s

open access: yes, 2020
This chapter focuses on social composition of the readers in early Soviet Russia (1917-1920s). The sociological data demonstrates readers' preferences and new conditions of functioning of institute of reading in Russia after the Bolshevik ...
Evgeny Dobrenko
core  

The Overseas Reception of Chinese Science Fiction Works from a Perspective of Western Interpretation Preference——A Case Study of Reader's Reception of Liu Cixin's The Three-Body Problem in the USA

open access: yesContemporary Social Sciences, 2018
The Three-Body Problem, written by Liu Cixin, won the 2015 Hugo Award for Best Novel, with over 200,000 copies in English already sold. This gure is hundreds of times the average sales volume of Chinese novels in the USA.
Liu Ge, Li Yun
doaj   +1 more source

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