Results 71 to 80 of about 1,775,381 (345)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The role of m6A RNA methylation in infectious diseases
Among over 170 known RNA modifications, N6-methyladenosine (m6A) stands out as the most ubiquitous and extensively studied modification, found in different cellular RNA.
Nidhi Yadav +3 more
doaj +1 more source
Insights into newly discovered marks and readers of epigenetic information
The field of chromatin biology has been advancing at an accelerated pace. Recent discoveries of previously uncharacterized sites and types of post-translational modifications (PTMs) and the identification of new sets of proteins responsible for the ...
F. Andrews, B. Strahl, T. Kutateladze
semanticscholar +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Self-translate to manipulate [PDF]
Translation involves the carrying-over of texts to target audiences that have at their disposal an established system of representation with its own norms for the production and consumption of knowledge vis-à-vis self, others, objects, and events.
Said Faiq
doaj +1 more source
Perceiving the epigenetic landscape through histone readers
Post-translational modifications (PTMs) of histones provide a fine-tuned mechanism for regulating chromatin structure and dynamics. PTMs can alter direct interactions between histones and DNA and serve as docking sites for protein effectors, or readers ...
C. Musselman +3 more
semanticscholar +1 more source
Personalising Learning: Exploring the principles and processes of the IEP for young, gifted readers [PDF]
This small-scale qualitative, action research study sought to establish the efficacy of using the Individualised Education Programme (IEP) as an assistive tool towards the differentiation of reading programmes for young, gifted and talented readers ...
Mazza-Davies, Laurie Lynn
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
N6-methyladenosine (m6A) is a widespread post-transcriptional modification of RNA in eukaryotes. The conserved YTH-domain-containing RNA binding protein has been widely reported to serve as a typical m6A reader in various species.
Han Wang +5 more
doaj +1 more source

