Results 161 to 170 of about 6,236,073 (332)
HOMESIDE—A home‐based family caregiver‐delivered music and reading intervention for people living with dementia: A randomised controlled trial [PDF]
, 2021 Felicity A. Baker +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Toward an Improved Understanding of Dyslexia: Reflections on a New Consensus Definition and Its Implications. [PDF]
DyslexiaMorsanyi K +6 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Consensus Without Clarity for Dyslexia Identification: A Commentary on Holden et al. [PDF]
DyslexiaMetsala JL +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Colloid cyst: an unusual cause of seizure [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2015 Dilli Ram Poudel +5 more
doaj +1 more source