Results 111 to 120 of about 1,982,301 (342)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Linguistically Balanced Tool for Reading Skills Assessment in Russian-Speaking Adults
Вопросы образованияReading impairments substantially reduce quality of life, that is why it is necessary to detect them timely, provide intervention programs, or provide special learning or working environment for people with reading impairments in case the intervention ...
Svetlana V. Dorofeeva, Yana A. Kokoreva
doaj +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
The construction of a dynamic assessment model of reading ability in secondary school students' English classroom [PDF]
Yugoslav Journal of Operations ResearchSecondary school students' reading ability in English classroom is an important ability for secondary school students' English learning, and it is also highly valued by teachers, parents as well as students.
Wang Hui
doaj +1 more source
From reading literature in secondary school to its learning assessment in the 12th year national exam [PDF]
, 2015 Maria Carolina Cerqueira Veloso Pereira da Costa +1 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Is there a difference between reading and oral comprehension at the end of the fundamental course?
PerspectivaOral comprehension has been largely overlooked compared to written comprehension, not only in research but also in teaching, especially in Brazil. To address this gap, the present study compared the comprehension of oral (OC) and written (WC) texts in ...
Lucilene Bender de Sousa +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source