Results 81 to 90 of about 1,982,301 (342)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The Instrument of Teaching Metacognition in Reading Classrooms: The ITMR

International Journal of Assessment Tools in Education, 2020
Limited influence of metacognition research in mainstream classrooms may stem from a lack of comprehensive pedagogy and/or inconsistent criteria assessing metacognition instruction.
Nesrin Ozturk
doaj   +1 more source

Experiments with discourse-level choices and readability [PDF]

, 2003
This paper reports on pilot experiments that are being used, together with corpus analysis, in the development of a Natural Language Generation (NLG) system, GIRL (Generator for Individual Reading Levels).
Osman, Liesl, Reiter, Ehud, Williams, Sandra   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Évaluation de la fluence en lecture : au-delà du nombre de mots correctement lus par minute

Repères
From Year 2 through to Year 9, national assessments use the number of words correctly read in one minute (WCPM) to assess fluency. However, the use of this measure is not in line with the definition of fluency, which includes precision and speed, as well
Erika Godde
doaj   +1 more source

Reading Comprehension Strategies in the ELA classroom [PDF]

, 2012
This research project analyzes reading comprehension strategies in the English/Language Arts classroom. The comprehension strategies implemented were as follows: “Read Write Pair Share,” “Exit Slips,” “Dialectical Journals,” and “Student Questioning for ...
Budynsky, Jenna
core   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

KWL and Homer\u27s Illiad. [PDF]

, 2013
As a student teacher I was disappointed at initial confusion by my World Literature students when we began reading Homer’s Iliad. I wanted to probe my students about the fascinating questions the story raises about the Greek culture, the qualities of a ...
Menke, Kristen
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The Influence of Local Politics on Educational Decisions

Current Issues in Education, 2012
This ex post facto, causal-comparative research study examined student reading performance data within a school district before and after a school district-wide decision to alter the reading curriculum in response to local political pressure from parents.
Gary Bigham, Jan Ray
doaj