Results 91 to 100 of about 2,009,338 (286)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Historicizing Romantic Sexuality [PDF]

open access: yes, 2006
This volume of Romantic Circles Praxis includes an editor's introduction by Richard C. Sha, essays by Richard C. Sha, Jonathan Loesberg, Elizabeth Fay, Jillian Hedy-Stevenson, Susan S. Lanser, Bradford K. Mudge, Daniel O'Quinn, David M.
Romantic Circles
core   +1 more source

Utilizing series books as a vehicle to cultivate motivation and reading development in literature circles [PDF]

open access: yes, 2018
The purpose of this study is to document the changes in student achievement, motivation, and engagement. The specific aim is to see what happens when series books are discussed in literature circles.
Guerci, Heather E.
core   +1 more source

TEACHING READING NARRATIVE READING BY USING LITERATURE CIRCLES STRATEGY TO THE TENTH GRADE STUDENTS OF SMAN 1 LEMPUING JAYA

open access: yesEdukasi: Jurnal Pendidikan dan Pengajaran, 2017
The objective of this study are to find out whether or not there is significant difference and significant improvement on the tenth grade students’ narrative reading achievement between those who are taught by using Literature Circles Strategy and those ...
nofitarina nofitarina
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Squaring the circle: exploring the use of reading circles to encourage law students to read [PDF]

open access: yes, 2017
Reading is the fundamental foundation of a law degree yet many students seem to avoid exploring beyond the lecture notes and core text. We wanted to encourage independent research, wide reading, active participation and used a new module on Inquests to ...
Rutherford, Helen, Taylor, Jennifer
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Literature Circles and Reading Comprehension

open access: yes, 2019
We will take a look at the relationship between literature circles and reading comprehension. The main focus of this research is to see how literature circles affect reading comprehension and to hopefully find that they are beneficial.
Crabtree, Deanna
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

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